TMPRSS2

TMPRSS2（Transmembrane Serine Protease 2）是一種跨膜絲氨酸蛋白酶，TMPRSS2主要存在于上皮細(xì)胞中，特別是在肺部、腸道和前列腺等組織中表達(dá)較高。它的一個重要作用是剪切和活化其他蛋白，尤其是病毒蛋白或其他蛋白前體。在病毒感染中，比如在SARS-CoV-2（導(dǎo)致COVID-19的病毒）感染中，TMPRSS2蛋白可以促進(jìn)病毒進(jìn)入宿主細(xì)胞。在COVID-19研究中，TMPRSS2被認(rèn)為參與了SARS-CoV-2病毒進(jìn)入上皮細(xì)胞的過程，因此針對TMPRSS2的研究可能有助于發(fā)展針對病毒入侵的治療方法。

熱銷產(chǎn)品

Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial (Active)

驗證數(shù)據(jù)

SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Recombinant Human TMPRSS2 His tag protein (CSB-YP023924HU) enzyme activity is measured by its ability to cleave fluorogenic peptide substrate(Boc-Gln-Ala-Arg-AMC), The Km is 21.93μM.

ELISA

Activity
Measured by Camostat Mesylate inhibit ratio on TMPRSS2 (CSB-YP023924HU), which can cleave fluorogenic peptide substrate (Boc-Gln-Ala-Arg-AMC). The Camostat Mesylate inhibit EC₅₀ is 0.03347-0.07945μM.

TMPRSS2 Antibody

TMPRSS2 Protein

TMPRSS2 Antibodies

TMPRSS2 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA971239	TMPRSS2 Antibody	Human	ELISA, WB

TMPRSS2 Proteins

TMPRSS2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023924HU	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial (Active)	Yeast
CSB-EP023924HU	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	E.coli
CSB-BP023924HU	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Baculovirus
CSB-MP023924HU	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Mammalian cell
CSB-EP023924HUa2	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	E.coli
CSB-EP023924HUe0	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	E.coli
CSB-YP023924HUa4	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Yeast
CSB-MP023924HUb0	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Mammalian cell
CSB-YP023924HU(M)c7	Recombinant Human Transmembrane protease serine 2 (TMPRSS2) (R255Q), partial	Yeast
CSB-YP023924HU(M)f3	Recombinant Human Transmembrane protease serine 2 (TMPRSS2) (R255Q), partial	Yeast
CSB-MP023924HU(M)b0	Recombinant Human Transmembrane protease serine 2 (TMPRSS2) (R255Q), partial (Active)	Mammalian cell
CSB-EP023924HU1	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	E.coli
CSB-EP023924HU1a2	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	E.coli
CSB-EP023924HU1e0	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	E.coli
CSB-YP023924HU1	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Yeast
CSB-YP023924HU1c7	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Yeast
CSB-YP023924HU1f3	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Yeast
CSB-MP023924HU1	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Mammalian cell
CSB-MP023924HU1b0	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	Mammalian cell
CSB-EP023924HU-B	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial,Biotinylated	E.coli
CSB-CF023924HU	Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial	in vitro E.coli expression system

TMPRSS2 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-BP884918MO CSB-MP884918MO CSB-EP884918MO-B	Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP884918MO	Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial	E.coli
CSB-YP884918MO	Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial	Yeast
CSB-YP884918MO	Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial	Yeast
CSB-YP884918MOc7	Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial	Yeast