TARDBP
TARDBP蛋白，也稱為TDP-43，是一種具有RRM1和RRM2的RNA結合因子，其結構包括N端的氨基末端、兩個RNA識別區以及富含甘氨酸的C端。該蛋白通過結合GU重復序列，調節RNA的剪接過程，對神經元存活和神經退行性疾病中的蛋白質功能至關重要。TARDBP蛋白的突變或異常聚集與多種神經退行性疾病如ALS和FTLD相關。雖然其具體的信號通路尚未完全明確，但研究表明，TARDBP可能與其他蛋白或分子相互作用，形成復雜的信號網絡，共同調控神經元的生存和功能，涉及細胞凋亡、自噬等信號轉導途徑。
熱銷產品
Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial
驗證數據
SDS
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TARDBP Antibodies
TARDBP for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA023129GA01HU | TARDBP Antibody | Human,Mouse,Rat,Zebrafish | ELISA,WB,IHC,IF,IP |
| CSB-PA621652ESR1HU | TARDBP Antibody | Human, Mouse | ELISA, WB, IHC, IP |
| CSB-PA023129EA01HU | TARDBP Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA023129EB01HU | TARDBP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA023129EC01HU | TARDBP Antibody, FITC conjugated | Human | |
| CSB-PA023129ED01HU | TARDBP Antibody, Biotin conjugated | Human | ELISA |
TARDBP Proteins
TARDBP Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP023129HU | Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial | E.coli |
| CSB-YP023129HU | Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial | Yeast |
| CSB-EP023129HUe0 | Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial | E.coli |
| CSB-EP023129HU(A4) | Recombinant Human TAR DNA-binding protein 43 (TARDBP) | E.coli |
| CSB-EP023129HU2 | Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial | E.coli |
| CSB-EP023129HU(A4)a0 | Recombinant Human TAR DNA-binding protein 43 (TARDBP) | E.coli |
TARDBP ELISA Kit
TARDBP ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E17007h | Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA kit | serum, plasma, cell culture supernates, cerebrospinal fluid (CSF) | 0.078 ng/mL |
