SH2B3
SH2B adapter protein 3 is a protein in humans that is encoded by SH2B3 gene. Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways mediated by Janus kinase (JAK) and receptor tyrosine kinases, including the receptors of insulin (INS), insulin-like growth factor I (IGF1), nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), platelet-derived growth factor (PDGF) and fibroblast growth factors (FGFs). In growth hormone (GH) signaling, autophosphorylated ('Tyr-813') JAK2 recruits SH2B1, which in turn is phosphorylated by JAK2 on tyrosine residues. These phosphotyrosines form potential binding sites for other signaling proteins.
SH2B3 Proteins
SH2B3 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP021208RA CSB-EP021208RA CSB-BP021208RA CSB-MP021208RA CSB-EP021208RA-B |
Recombinant Rat SH2B adapter protein 3 (Sh2b3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SH2B3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP021208MO CSB-EP021208MO CSB-BP021208MO CSB-MP021208MO CSB-EP021208MO-B |
Recombinant Mouse SH2B adapter protein 3 (Sh2b3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SH2B3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP892371HU CSB-EP892371HU CSB-BP892371HU CSB-MP892371HU CSB-EP892371HU-B |
Recombinant Human SH2B adapter protein 3 (SH2B3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
