RPTOR
Regulatory-associated protein of mTOR is a protein in humans that is encoded by RPTOR gene. Involved in the control of the mammalian target of rapamycin complex 1 (mTORC1) activity which regulates cell growth and survival, and autophagy in response to nutrient and hormonal signals; functions as a scaffold for recruiting mTORC1 substrates. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.
RPTOR Antibodies
RPTOR for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA839774LA01HU | RPTOR Antibody | Human | ELISA, IHC, IF |
| CSB-PA839774LB01HU | RPTOR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA839774LC01HU | RPTOR Antibody, FITC conjugated | Human | |
| CSB-PA839774LD01HU | RPTOR Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA581950A0HU | RPTOR Recombinant Monoclonal Antibody | Human | ELISA, IHC |
RPTOR Proteins
RPTOR Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP817010MO CSB-EP817010MO CSB-BP817010MO CSB-MP817010MO CSB-EP817010MO-B |
Recombinant Mouse Regulatory-associated protein of mTOR (Rptor), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPTOR Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP839774HU CSB-EP839774HU CSB-BP839774HU CSB-MP839774HU CSB-EP839774HU-B |
Recombinant Human Regulatory-associated protein of mTOR (RPTOR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
