PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform is a protein in humans that is encoded by PIK3CB gene. Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion and aggregation.
PIK3CB Antibodies
PIK3CB for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA017999GA01HU | PIK3CB Antibody | Human | ELISA,WB |
| CSB-PA110424 | PIK3CB Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA017999LA01HU | PIK3CB Antibody | Human | ELISA, IF |
| CSB-PA017999LB01HU | PIK3CB Antibody, HRP conjugated | Human | ELISA |
| CSB-PA017999LC01HU | PIK3CB Antibody, FITC conjugated | Human | |
| CSB-PA017999LD01HU | PIK3CB Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA240122A0HU | PIK3CB Recombinant Monoclonal Antibody | Human | ELISA, WB, IP |
PIK3CB Proteins
PIK3CB Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP017999HU CSB-EP017999HU CSB-BP017999HU CSB-MP017999HU CSB-EP017999HU-B |
Recombinant Human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3CB Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP806903MO CSB-EP806903MO CSB-BP806903MO CSB-MP806903MO CSB-EP806903MO-B |
Recombinant Mouse Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Pik3cb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
