PF4
PF4，全稱為血小板因子4，是一種存在于血小板α顆粒中的蛋白質(zhì)，也被稱為血小板因子4或CXCL4。PF4在止血和血栓形成過程中發(fā)揮著重要作用，能夠抑制內(nèi)皮細(xì)胞增殖、遷移和血管生成，調(diào)節(jié)細(xì)胞凋亡，擴(kuò)大NK細(xì)胞炎癥應(yīng)答等。PF4能夠與多種細(xì)胞表面的糖胺多糖結(jié)合，如肝素，從而發(fā)揮其生物學(xué)功能。此外，PF4還能降低正常造血干細(xì)胞對化療藥物的敏感性，而不影響腫瘤細(xì)胞對化療藥物的敏感性，其機(jī)制是PF4可逆性地抑制細(xì)胞增殖，將細(xì)胞阻止在S期，同時(shí)還保持細(xì)胞的生存力和活力。因此，PF4可作為造血細(xì)胞的防護(hù)劑用于腫瘤臨床治療中。近年來研究發(fā)現(xiàn)，血清PF4水平可作為胰腺癌病人存活和靜脈血栓栓塞形成的獨(dú)立指標(biāo)，其開發(fā)具有很好的科研和臨床價(jià)值。目前，PF4的測定不僅作為體內(nèi)高凝狀態(tài)的敏感指標(biāo)，而且在多種疾患的診斷和預(yù)后的判斷中，PF4的測定也有相當(dāng)重要的臨床意義。
熱銷產(chǎn)品
Human Platelet factor 4 variant(PF4V1) ELISA kit (CSB-EL017810HU)
驗(yàn)證數(shù)據(jù)
貨號：CSB-EL017810HU
規(guī)格：96T/48T
靈敏度：0.156 ng/mL
檢測范圍：0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
PF4 Antibodies
PF4 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA958757 | PF4 Antibody | Human,Rat | IHC,ELISA |
| CSB-PA017809LA01HU | PF4 Antibody | Human | ELISA, IHC |
| CSB-PA017809LB01HU | PF4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA017809LC01HU | PF4 Antibody, FITC conjugated | Human | |
| CSB-PA017809LD01HU | PF4 Antibody, Biotin conjugated | Human | ELISA |
PF4 Proteins
PF4 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017809RB CSB-EP017809RB CSB-BP017809RB CSB-MP017809RB CSB-EP017809RB-B |
Recombinant Rabbit Platelet factor 4 (PF4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PF4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017810HU CSB-EP017810HU CSB-BP017810HU CSB-MP017810HU CSB-EP017810HU-B |
Recombinant Human Platelet factor 4 variant (PF4V1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP017809HU CSB-MP017809HU CSB-EP017809HU-B |
Recombinant Human Platelet factor 4 (PF4) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000661HU | Recombinant Human Platelet factor 4 protein (PF4) | E.Coli |
PF4 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP017809PI CSB-MP017809PI CSB-EP017809PI-B |
Recombinant Pig Platelet factor 4 (PF4) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PF4 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017809SH CSB-EP017809SH CSB-BP017809SH CSB-MP017809SH CSB-EP017809SH-B |
Recombinant Sheep Platelet factor 4 (PF4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PF4 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017809BO CSB-EP017809BO CSB-BP017809BO CSB-MP017809BO CSB-EP017809BO-B |
Recombinant Bovine Platelet factor 4 (PF4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PF4 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017809RA CSB-EP017809RA CSB-BP017809RA CSB-MP017809RA CSB-EP017809RA-B |
Recombinant Rat Platelet factor 4 (Pf4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PF4 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017809MO CSB-BP017809MO CSB-MP017809MO CSB-EP017809MO-B |
Recombinant Mouse Platelet factor 4 (Pf4) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001101MO | Recombinant Mouse Platelet factor 4 (Pf4) | E.Coli |
| CSB-EP017809MO | Recombinant mouse platelet factor 4 (Pf4) | E.coli |
PF4 ELISA Kit
PF4 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07882h | Human Platelet Factor 4,PF-4 ELISA Kit | serum, plasma, tissue homogenates | 1.56 ng/mL |
| CSB-EL017810HU | Human Platelet factor 4 variant(PF4V1) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 0.156 ng/mL |
PF4 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07884m | Mouse Platelet Factor 4,PF-4 ELISA Kit | serum, plasma, tissue homogenates | 1.603 ng/mL |
PF4 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07885r | Rat Platelet Factor 4,PF-4 ELISA Kit | serum, plasma, tissue homogenates | 0.039 μg/mL |
PF4 ELISA Kit for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL017809SH | Sheep Platelet factor 4(PF4) ELISA kit | Request Information |
