PDCD1LG2
PDCD1LG2，即程序性細(xì)胞死亡1配體2，別名PD-L2、Btdc、PDL2、CD273等。它是由人類PDCD1LG2基因編碼的蛋白質(zhì)，該基因位于9號(hào)染色體上。PDCD1LG2是免疫受體CD28家族的成員之一，主要通過(guò)與PD-1結(jié)合發(fā)揮免疫調(diào)節(jié)作用，從而參與抑制T細(xì)胞的激活和增殖，進(jìn)而在免疫耐受和免疫逃逸中發(fā)揮作用。PD-L2在免疫細(xì)胞如樹(shù)突細(xì)胞和巨噬細(xì)胞以及非免疫細(xì)胞如腫瘤細(xì)胞中的表達(dá)，有助于調(diào)節(jié)免疫應(yīng)答和促進(jìn)腫瘤免疫逃逸。PDCD1LG2的生物學(xué)意義在于其在腫瘤免疫逃逸中的作用，是癌癥免疫治療的重要靶點(diǎn)，其表達(dá)水平與多種腫瘤的預(yù)后相關(guān)。
熱銷產(chǎn)品
Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial (CSB-EP017667HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PDCD1LG2 Antibody (CSB-PA511971)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA511971(PDCD1LG2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA511971(PDCD1LG2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
PDCD1LG2 Antibodies
PDCD1LG2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA944824 | PDCD1LG2 Antibody | Human | ELISA,IHC |
| CSB-PA511971 | PDCD1LG2 Antibody | Human | ELISA,IHC |
| CSB-PA017667EA01HU | PDCD1LG2 Antibody | Human | ELISA |
| CSB-PA017667EB01HU | PDCD1LG2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA017667EC01HU | PDCD1LG2 Antibody, FITC conjugated | Human | |
| CSB-PA017667ED01HU | PDCD1LG2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-MA017667A0m | PD-L2 Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC, IP |
PDCD1LG2 Proteins
PDCD1LG2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017667HU CSB-BP017667HU CSB-MP017667HU CSB-EP017667HU-B |
Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017667HU | Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial | E.coli |
| CSB-MP017667HU1 | Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial | Mammalian cell |
PDCD1LG2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017667MO CSB-EP017667MO CSB-BP017667MO CSB-MP017667MO CSB-EP017667MO-B |
Recombinant Mouse Programmed cell death 1 ligand 2 (Pdcd1lg2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDCD1LG2 ELISA Kit
PDCD1LG2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL017667HU | Human Programmed cell death 1 ligand 2(PDCD1LG2) ELISA kit | serum, plasma, tissue homogenates. | 0.11 ng/ml |
