MOB1A
MOB kinase activator 1A is a protein in humans that is encoded by MOB1A gene. Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.
MOB1A Antibodies
MOB1A for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA014696GA01HU | MOB1A Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA872519HA01HU | MOB1A Antibody | Human | ELISA, WB, IHC, IF, IP |
| CSB-PA872519HC01HU | MOB1A Antibody, FITC conjugated | Human | |
| CSB-PA240239 | MOB1A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA932807 | MOB1A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
MOB1A Proteins
MOB1A Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP666219RA CSB-EP666219RA CSB-BP666219RA CSB-MP666219RA CSB-EP666219RA-B |
Recombinant Rat MOB kinase activator 1A (Mob1a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MOB1A Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP735761PYX CSB-EP735761PYX CSB-BP735761PYX CSB-MP735761PYX CSB-EP735761PYX-B |
Recombinant Pongo abelii MOB kinase activator 1A (MOB1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MOB1A Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP838745MO CSB-EP838745MO CSB-BP838745MO CSB-MP838745MO CSB-EP838745MO-B |
Recombinant Mouse MOB kinase activator 1A (Mob1a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MOB1A Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP872519HU CSB-BP872519HU CSB-MP872519HU CSB-EP872519HU-B |
Recombinant Human MOB kinase activator 1A (MOB1A) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP872519HU | Recombinant Human MOB kinase activator 1A (MOB1A) | E.coli |
