LOX
LOX，lysyloxidase，即賴氨酰氧化酶。LOX是一種分泌型的銅依賴性胺氧化酶，由人類LOX基因編碼，該基因?qū)儆谫嚢滨Ｑ趸讣易澹瑢τ诮Y(jié)締組織的形成至關(guān)重要。LOX的作用機制在于催化膠原蛋白和彈性蛋白的共價鍵形成，這一過程需要銅離子的參與，使得膠原蛋白和彈性蛋白上的特殊氨基酸殘基氧化，從而形成共價鍵。LOX不僅在正常組織發(fā)育、組織維持和細胞命運決定中發(fā)揮作用，還與多種病理過程相關(guān)，包括腫瘤進展、血管生成、糖尿病性新血管形成、成骨分化、韌帶重塑等。LOX活性異常與多種疾病相關(guān)，包括膠質(zhì)母細胞瘤、多囊卵巢綜合征、胎兒膜破裂等。在發(fā)炎情況下，LOX在減少與糖尿病、骨質(zhì)疏松癥和類風濕性關(guān)節(jié)炎相關(guān)的病理過程中起作用。
熱銷產(chǎn)品
Recombinant Human Protein-lysine 6-oxidase (LOX), partial (CSB-EP013038HU1a0)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
LOX Antibody (CSB-PA16909A0Rb)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: A549 whole cell lysate, MCF-7 whole cell lysate
All lanes: LOX antibody at 3.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47 kDa
Observed band size: 47 kDa
IHC image of CSB-PA16909A0Rb diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Human Protein-lysine 6-oxidase(LOX) ELISA kit (CSB-E16376h)
驗證數(shù)據(jù)
貨號：CSB-E16376h
規(guī)格：96T/48T
靈敏度：0.156 ng/mL
檢測范圍：0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
LOX Antibodies
LOX for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA013038GA01HU | LOX Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA16909B0Rb | LOX Antibody, HRP conjugated | Human | ELISA |
| CSB-PA16909A0Rb | LOX Antibody | Human | ELISA, WB, IHC |
| CSB-PA808676 | LOX Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA130669 | LOX Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA061510 | LOX Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA013038LA01HU | LOX Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-PA013038LB01HU | LOX Antibody, HRP conjugated | Human | ELISA |
| CSB-PA013038LC01HU | LOX Antibody, FITC conjugated | Human | |
| CSB-PA013038LD01HU | LOX Antibody, Biotin conjugated | Human | ELISA |
LOX for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA013038LA01RA | Lox Antibody | Rat, Human | ELISA, WB |
| CSB-PA013038LD01RA | Lox Antibody, Biotin conjugated | Rat | ELISA |
LOX Proteins
LOX Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013038CH CSB-EP013038CH CSB-BP013038CH CSB-MP013038CH CSB-EP013038CH-B |
Recombinant Chicken Protein-lysine 6-oxidase (LOX) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LOX Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013038HU CSB-MP013038HU CSB-EP013038HU-B |
Recombinant Human Protein-lysine 6-oxidase (LOX) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP013038HU1a0 | Recombinant Human Protein-lysine 6-oxidase (LOX), partial | E.coli |
| CSB-EP013038HU | Recombinant Human Protein-lysine 6-oxidase (LOX) | E.coli |
| CSB-BP013038HU | Recombinant Human Protein-lysine 6-oxidase (LOX) | Baculovirus |
| CSB-EP013038HU1 | Recombinant Human Protein-lysine 6-oxidase (LOX), partial | E.coli |
LOX Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013038BO CSB-EP013038BO CSB-BP013038BO CSB-MP013038BO CSB-EP013038BO-B |
Recombinant Bovine Protein-lysine 6-oxidase (LOX) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LOX Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013038PI CSB-EP013038PI CSB-BP013038PI CSB-MP013038PI CSB-EP013038PI-B |
Recombinant Pig Protein-lysine 6-oxidase (LOX) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LOX Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013038MO CSB-EP013038MO CSB-MP013038MO CSB-EP013038MO-B |
Recombinant Mouse Protein-lysine 6-oxidase (Lox) | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP013038MO | Recombinant Mouse Protein-lysine 6-oxidase (Lox) | Baculovirus |
LOX Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013038RA CSB-BP013038RA CSB-MP013038RA CSB-EP013038RA-B |
Recombinant Rat Protein-lysine 6-oxidase (Lox) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP013038RA | Recombinant Rat Protein-lysine 6-oxidase (Lox) | E.coli |
LOX Proteins for Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011660NHA CSB-EP011660NHA CSB-BP011660NHA CSB-MP011660NHA CSB-EP011660NHA-B |
Recombinant Neurospora crassa L-amino-acid oxidase (lox), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LOX Proteins for Pseudomonas aeruginosa
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP823295EZW CSB-EP823295EZW CSB-BP823295EZW CSB-MP823295EZW CSB-EP823295EZW-B |
Recombinant Oleic acid lipoxygenase (lox), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LOX ELISA Kit
LOX ELISA Kit for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E15813p | Pig Lysyl Oxidase ELISA Kit | serum, plasma, tissue homogenates | 0.39 ng/mL |
LOX ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E16376h | Human Protein-lysine 6-oxidase(LOX) ELISA kit | serum, plasma, tissue homogenates | 0.156 ng/mL |
