KSR2
Kinase suppressor of Ras 2 is a protein in humans that is encoded by KSR2 gene. Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
KSR2 Antibodies
KSR2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA581207 | KSR2 Antibody | Human,Mouse | ELISA,WB,IF |
| CSB-PA008904 | KSR2 Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA012696LA01HU | KSR2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA012696LB01HU | KSR2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA012696LC01HU | KSR2 Antibody, FITC conjugated | Human | |
| CSB-PA012696LD01HU | KSR2 Antibody, Biotin conjugated | Human | ELISA |
KSR2 Proteins
KSR2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP012696HU CSB-EP012696HU CSB-BP012696HU CSB-MP012696HU CSB-EP012696HU-B |
Recombinant Human Kinase suppressor of Ras 2 (KSR2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KSR2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP012696MO CSB-EP012696MO CSB-BP012696MO CSB-MP012696MO CSB-EP012696MO-B |
Recombinant Mouse Kinase suppressor of Ras 2 (Ksr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
