KCNMA1
Calcium-activated potassium channel subunit alpha-1 is a protein in humans that is encoded by KCNMA1 gene. Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
KCNMA1 Antibodies
KCNMA1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA003200 | KCNMA1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA782845 | KCNMA1 Antibody | Human | ELISA,IHC |
| CSB-PA275132 | KCNMA1 Antibody | Human | ELISA,IHC |
| CSB-PA614255LA01HU | KCNMA1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA614255LB01HU | KCNMA1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA614255LC01HU | KCNMA1 Antibody, FITC conjugated | Human | |
| CSB-PA614255LD01HU | KCNMA1 Antibody, Biotin conjugated | Human | ELISA |
KCNMA1 Proteins
KCNMA1 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012077MOW CSB-EP012077MOW CSB-BP012077MOW CSB-MP012077MOW CSB-EP012077MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KCNMA1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012077PI CSB-EP012077PI CSB-BP012077PI CSB-MP012077PI CSB-EP012077PI-B |
Recombinant Pig Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KCNMA1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP614255HU CSB-BP614255HU CSB-MP614255HU CSB-EP614255HU-B |
Recombinant Human Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP614255HU | Recombinant Human Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | E.coli |
| CSB-EP614255HUe1 | Recombinant Human Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | E.coli |
KCNMA1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP630674DO CSB-EP630674DO CSB-BP630674DO CSB-MP630674DO CSB-EP630674DO-B |
Recombinant Dog Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KCNMA1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP637894BO CSB-EP637894BO CSB-BP637894BO CSB-MP637894BO CSB-EP637894BO-B |
Recombinant Bovine Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KCNMA1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP723487RA CSB-EP723487RA CSB-BP723487RA CSB-MP723487RA CSB-EP723487RA-B |
Recombinant Rat Calcium-activated potassium channel subunit alpha-1 (Kcnma1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KCNMA1 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP803832CH CSB-EP803832CH CSB-BP803832CH CSB-MP803832CH CSB-EP803832CH-B |
Recombinant Chicken Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KCNMA1 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP849564XBE CSB-EP849564XBE CSB-BP849564XBE CSB-MP849564XBE CSB-EP849564XBE-B |
Recombinant Xenopus laevis Calcium-activated potassium channel subunit alpha-1 (kcnma1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KCNMA1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP859376RB CSB-EP859376RB CSB-BP859376RB CSB-MP859376RB CSB-EP859376RB-B |
Recombinant Rabbit Calcium-activated potassium channel subunit alpha-1 (KCNMA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
