IRAK1
Interleukin-1 receptor-associated kinase 1 is a protein in humans that is encoded by IRAK1 gene. Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1.
IRAK1 Antibodies
IRAK1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA274948 | Phospho-IRAK1 (Ser376) Antibody | Human | ELISA,IHC |
| CSB-PA101009 | IRAK1 Antibody | Human | ELISA,IHC |
| CSB-PA003061 | IRAK1 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA011231 | Phospho-IRAK1 (T209) Antibody | Human | WB, ELISA |
| CSB-PA011232 | Phospho-IRAK1 (T100) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA011233 | Phospho-IRAK1 (S376) Antibody | Human | IHC, ELISA |
| CSB-PA011234 | Phospho-IRAK1 (T387) Antibody | Human,Mouse,Rat | IF, ELISA |
| CSB-PA011235 | IRAK1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA011236 | IRAK1 Antibody | Human | IHC, ELISA |
IRAK1 Proteins
IRAK1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011808HU CSB-EP011808HU CSB-BP011808HU CSB-MP011808HU CSB-EP011808HU-B |
Recombinant Human Interleukin-1 receptor-associated kinase 1 (IRAK1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IRAK1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011808MO CSB-EP011808MO CSB-BP011808MO CSB-MP011808MO CSB-EP011808MO-B |
Recombinant Mouse Interleukin-1 receptor-associated kinase 1 (Irak1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IRAK1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011808BO CSB-EP011808BO CSB-BP011808BO CSB-MP011808BO CSB-EP011808BO-B |
Recombinant Bovine Interleukin-1 receptor-associated kinase 1 (IRAK1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
