GPC3
GPC3是一種糖蛋白，具有特定的蛋白質結構，其中包括一個胞外糖基化的部分和一個胞漿部分。可以與多種生長因子、信號分子和受體相互作用，從而影響細胞信號傳導通路。它可以促進或抑制特定信號通路的激活，因此對于細胞生長、增殖和分化等過程具有調節作用。在胚胎發育中，GPC3對于正常器官和組織的形成至關重要。它在特定發育階段參與胚胎體軸的建立、四肢發育和器官的分化。 GPC3異常表達會影響疾病的發生發展，研究GCP3的功能和調節機制對于理解疾病的發病機制和開發相關治療方法具有重要意義。
更多相關閱讀：靶向GPC3在肝癌中初顯成效，未來聯合治療潛力更大
熱銷產品
● Recombinant Human Glypican-3(GPC3)(G537R),partial (Active) CSB-MP009705HU(M)
驗證數據
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Activity: Measured by its binding ability in a functional ELISA. Immobilized human GPC3 (G537R) at 5 μg/ml can bind Anti-GPC3 recombinant antibody, the EC50 is 4.739-7.092 ng/ml.
● GPC3 Recombinant Monoclonal Antibody CSB-RA009705A0HU
驗證數據
Western Blot
Positive WB detected in: 293 whole cell lysate, K562 whole cell lysate All lanes: GPC3 antibody at 0.9μg/ml. Secondary, Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66, 60, 69 KDa Observed band size: 66 KDa
Immunofluorescence staining of HepG2 cells with CSB-RA009705A0HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
● CT26/Human GPC3 Stable Cell Line CSB-SC009705HU2
驗證數據
Untransfected CT26 cells (green line) and transfected Human GPC3 CT26 Stable cells (red line) were stained with anti-GPC3 antibody(CSB-RA009705A1HU) (2µg/1*106cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
GPC3 Antibodies
GPC3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA009705GA01HU | GPC3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA005135 | GPC3 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-RA009705A0HU | GPC3 Recombinant Monoclonal Antibody | Human | ELISA, WB, IF |
| CSB-PA12749A0Rb | GPC3 Antibody | Human | ELISA, IF |
| CSB-PA12749B0Rb | GPC3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA12749C0Rb | GPC3 Antibody, FITC conjugated | Human | |
| CSB-PA12749D0Rb | GPC3 Antibody, Biotin conjugated | Human | ELISA |
| CSB-MA009705A0m | GPC3 Monoclonal Antibody | Human | ELISA, WB, FC |
| CSB-RA009705A1HU | GPC3 Recombinant Monoclonal Antibody | Human | ELISA |
| CSB-RA009705MA1HU | GPC3 Recombinant Monoclonal Antibody | Human | ELISA, FC |
GPC3 Proteins
GPC3 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009705RA | Recombinant Rat Glypican-3 (Gpc3), partial | Yeast |
| CSB-EP009705RA CSB-BP009705RA CSB-MP009705RA CSB-EP009705RA-B |
Recombinant Rat Glypican-3 (Gpc3), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPC3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009705HU CSB-EP009705HU CSB-BP009705HU CSB-EP009705HU-B |
Recombinant Human Glypican-3 (GPC3), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP005371HU | Recombinant Human Glypican-3 (GPC3), partial (Active) | Mammalian cell |
| CSB-MP009705HU(M) | Recombinant Human Glypican-3 (GPC3) (G537R), partial (Active) | Mammalian cell |
| CSB-MP009705HU(M2) | Recombinant Human Glypican-3 (GPC3)(S359F), partial (Active) | Mammalian cell |
GPC3 Proteins for Pan troglodytes (Chimpanzee)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009705EQV CSB-EP009705EQV CSB-BP009705EQV CSB-EP009705EQV-B |
Recombinant Pan troglodytes Glypican-3 (GPC3), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP009705EQV | Recombinant Pan troglodytes Glypican-3 (GPC3) | Mammalian cell |
GPC3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP804039MO CSB-EP804039MO CSB-BP804039MO CSB-MP804039MO CSB-EP804039MO-B |
Recombinant Mouse Glypican-3 (Gpc3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GPC3 ELISA Kit
GPC3 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E11333h | Human Glypican-3,GPC-3 ELISA Kit | serum, urine, cell culture supernates | 0.156 ng/mL |
GPC3 ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E15877m | Mouse Glypican-3(GPC-3)ELISA Kit | serum, plasma, cell culture supernates | 0.78 ng/mL |
GPC3 ELISA Kit for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL009705RA | Rat Glypican-3(GPC3) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
