GPBAR1
GPBAR1，即G蛋白偶聯膽汁酸受體1，別名TGR5、GPCR19、hGPCR19、M-BAR、BG37等。它來源于人體細胞內的基因表達，是G蛋白偶聯受體家族的一員。GPBAR1的作用機制主要通過識別并結合膽汁酸，激活下游信號通路，從而參與代謝調控、炎癥反應和能量平衡等生理過程。在生物學意義上，GPBAR1對于維持機體內環境穩定、預防代謝性疾病和炎癥性疾病具有重要意義，同時也是藥物研發的重要靶點之一。
熱銷產品
Recombinant Human?G-protein?coupled?bile?acid?receptor?1 (GPBAR1) (CSB-CF819471HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GPBAR1 Antibody (CSB-PA819471LA01HU)
驗證數據
Western Blot
Positive WB detected in: Mouse kidney tissue
All lanes: GPBAR1 antibody at 6μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 36 kDa
Observed band size: 36 kDa
IHC image of CSB-PA819471LA01HU diluted at 1:300 and staining in paraffin-embedded human bladder cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of 293 cells with CSB-PA819471LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Human G protein-coupled bile acid receptor 1(GPBAR1) ELISA Kit (CSB-E13937h)
驗證數據
貨號：CSB-E13937h
規格：96T/48T
靈敏度：0.039 ng/mL
檢測范圍：0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
GPBAR1 Antibodies
GPBAR1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA007456 | GPBAR1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA819471LA01HU | GPBAR1 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA819471LB01HU | GPBAR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA819471LC01HU | GPBAR1 Antibody, FITC conjugated | Human | |
| CSB-PA819471LD01HU | GPBAR1 Antibody, Biotin conjugated | Human | ELISA |
GPBAR1 Proteins
GPBAR1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP767305RA1 CSB-EP767305RA1 CSB-BP767305RA1 CSB-MP767305RA1 CSB-EP767305RA1-B |
Recombinant Rat G-protein coupled bile acid receptor 1 (Gpbar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF767305RA | Recombinant Rat G-protein coupled bile acid receptor 1 (Gpbar1) | in vitro E.coli expression system |
GPBAR1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP768106RB1 CSB-EP768106RB1 CSB-BP768106RB1 CSB-MP768106RB1 CSB-EP768106RB1-B |
Recombinant Rabbit G-protein coupled bile acid receptor 1 (GPBAR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF768106RB | Recombinant Rabbit G-protein coupled bile acid receptor 1 (GPBAR1) | in vitro E.coli expression system |
GPBAR1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP769663BO1 CSB-EP769663BO1 CSB-BP769663BO1 CSB-MP769663BO1 CSB-EP769663BO1-B |
Recombinant Bovine G-protein coupled bile acid receptor 1 (GPBAR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF769663BO | Recombinant Bovine G-protein coupled bile acid receptor 1 (GPBAR1) | in vitro E.coli expression system |
GPBAR1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP773890MO1 CSB-EP773890MO1 CSB-BP773890MO1 CSB-MP773890MO1 CSB-EP773890MO1-B |
Recombinant Mouse G-protein coupled bile acid receptor 1 (Gpbar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF773890MO | Recombinant Mouse G-protein coupled bile acid receptor 1 (Gpbar1) | in vitro E.coli expression system |
GPBAR1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP819471HU1 CSB-BP819471HU1 CSB-MP819471HU1 CSB-EP819471HU1-B |
Recombinant Human G-protein coupled bile acid receptor 1 (GPBAR1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF819471HU | Recombinant Human?G-protein?coupled?bile?acid?receptor?1 (GPBAR1) | in vitro E.coli expression system |
| CSB-EP819471HU1 | Recombinant Human G-protein coupled bile acid receptor 1 (GPBAR1), partial | E.coli |
| CSB-MP819471HU | Recombinant Human G-protein coupled bile acid receptor 1 (GPBAR1)-VLPs | Mammalian cell |
GPBAR1 ELISA Kit
GPBAR1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13937h | Human G protein-coupled bile acid receptor 1(GPBAR1) ELISA Kit | serum, plasma | 0.039 ng/mL |
