DSG2
DSG2(Desmoglein-2)，是一種細(xì)胞粘附蛋白，屬于鈣黏蛋白家族的一員。主要在上皮細(xì)胞中表達，如皮膚、心臟、肺、腸道等組織。DSG2的結(jié)構(gòu)特點包括外部區(qū)域和細(xì)胞膜跨膜區(qū)。外部區(qū)域包含多個結(jié)構(gòu)域，其中包括多個鈣離子結(jié)合位點，這些結(jié)構(gòu)域有助于DSG2與其他細(xì)胞間連接蛋白（如其他DSG蛋白或Plakophilin）相互作用，形成一種稱為"橋粒"（desmosomes）的連接結(jié)構(gòu)。 這種"橋粒"連接可以使上皮細(xì)胞緊密連接在一起，增強組織的結(jié)構(gòu)穩(wěn)定性，并提供細(xì)胞間的強大黏附力。這對于維持組織的完整性和穩(wěn)定性至關(guān)重要，尤其是在受到外部力量時，如心臟的搏動、皮膚的拉伸等情況下，它可以使上皮組織具有強大的耐受力。DSG2的功能異常可能導(dǎo)致一些疾病。例如，某些遺傳性皮膚疾病和心臟病與DSG2的突變或異常表達有關(guān)。
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熱銷產(chǎn)品
● DSG2 Recombinant Monoclonal Antibody CSB-RA622752MA1HU
驗證數(shù)據(jù)
The Binding Activity of DSG2 with anti-DSG2 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DSG2 (CSB-MP622752HU) at 2 μg/mL can bind Anti-DSG2 recombinant antibody，the EC50 is 20.26-38.00 ng/mL
● Recombinant Human Desmoglein-2(DSG2),partial (Active) CSB-MP622752HU
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DSG2 at 2μg/mL can bind Anti-DSG2 recombinant antibody (CSB-RA622752MA1HU)， the EC50 is 20.26-38.00 ng/mL
DSG2 Antibodies
DSG2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007204GA01HU | DSG2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA007839 | DSG2 Antibody | Human | WB, ELISA |
| CSB-PA025645 | DSG2 Antibody | Human | ELISA,IHC |
| CSB-PA401715 | DSG2 Antibody | Human | ELISA,IHC |
| CSB-PA622752LA01HU | DSG2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA622752LB01HU | DSG2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA622752LC01HU | DSG2 Antibody, FITC conjugated | Human | |
| CSB-PA622752LD01HU | DSG2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA622752MA1HU | DSG2 Recombinant Monoclonal Antibody | Human | ELISA |
DSG2 Proteins
DSG2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007204MO CSB-BP007204MO CSB-MP007204MO CSB-EP007204MO-B |
Recombinant Mouse Desmoglein-2 (Dsg2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP007204MO | Recombinant Mouse Desmoglein-2 (Dsg2), partial | E.coli |
DSG2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP622752HU CSB-EP622752HU CSB-EP622752HU-B |
Recombinant Human Desmoglein-2 (DSG2), partial | Yeast E.coli In Vivo Biotinylation in E.coli |
| CSB-EP622752HUb1 | Recombinant Human Desmoglein-2 (DSG2), partial | E.coli |
| CSB-BP622752HU | Recombinant Human Desmoglein-2 (DSG2), partial | Baculovirus |
| CSB-EP622752HUa0 | Recombinant Human Desmoglein-2 (DSG2), partial | E.coli |
| CSB-EP622752HUb0 | Recombinant Human Desmoglein-2 (DSG2), partial | E.coli |
| CSB-MP622752HU | Recombinant Human Desmoglein-2 (DSG2), partial (Active) | Mammalian cell |
