DRD2
DRD2，即多巴胺受體D2，別名D(2 dopamine receptor、Dopamine D2 receptor。它是一種G蛋白偶聯(lián)受體，由人體細(xì)胞自身的DRD2基因編碼，主要在大腦中表達(dá)，尤其在基底神經(jīng)節(jié)等區(qū)域。DRD2的作用機(jī)制主要是通過與多巴胺等配體結(jié)合，通過G蛋白抑制腺苷酸環(huán)化酶的活性，進(jìn)而影響細(xì)胞內(nèi)的cAMP水平和蛋白激酶A（PKA）的活性，參與調(diào)節(jié)多種生理過程。DRD2參與調(diào)節(jié)運(yùn)動控制、認(rèn)知功能、情緒反應(yīng)等多種生理過程。DRD2的活性也與多種疾病的發(fā)生發(fā)展密切相關(guān)，如帕金森病、精神分裂癥、Tourette綜合癥、藥物成癮等。此外，DRD2是多種藥物作用的靶點(diǎn)，包括抗精神病藥物和一些治療帕金森病的藥物。研究表明，DRD2的某些突變可能與肌張力障礙相關(guān) 。
熱銷產(chǎn)品
Recombinant Human D (2) dopamine receptor (DRD2), partial (CSB-EP007179HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
DRD2 Antibodies
DRD2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007179GA01HU | DRD2 Antibody | Human,Mouse,Rat | ELISA,WB |
DRD2 Proteins
DRD2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007179HU1 CSB-BP007179HU1 CSB-MP007179HU1 CSB-EP007179HU1-B |
Recombinant Human D (2) dopamine receptor (DRD2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007179HU | Recombinant Human D (2) dopamine receptor (DRD2) | in vitro E.coli expression system |
| CSB-EP007179HU1 | Recombinant Human D (2) dopamine receptor (DRD2), partial | E.coli |
DRD2 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007179BO1 CSB-EP007179BO1 CSB-BP007179BO1 CSB-MP007179BO1 CSB-EP007179BO1-B |
Recombinant Bovine D (2) dopamine receptor (DRD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007179BO | Recombinant Bovine D (2) dopamine receptor (DRD2) | in vitro E.coli expression system |
DRD2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007179MO1 CSB-EP007179MO1 CSB-BP007179MO1 CSB-MP007179MO1 CSB-EP007179MO1-B |
Recombinant Mouse D (2) dopamine receptor (Drd2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007179MO | Recombinant Mouse D (2) dopamine receptor (Drd2) | in vitro E.coli expression system |
DRD2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007179RA1 CSB-EP007179RA1 CSB-BP007179RA1 CSB-MP007179RA1 CSB-EP007179RA1-B |
Recombinant Rat D (2) dopamine receptor (Drd2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007179RA | Recombinant Rat D (2) dopamine receptor (Drd2) | in vitro E.coli expression system |
DRD2 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP346012DSU1 CSB-EP346012DSU1 CSB-BP346012DSU1 CSB-MP346012DSU1 CSB-EP346012DSU1-B |
Recombinant Chlorocebus aethiops D (2) dopamine receptor, partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF346012DSU | Recombinant Chlorocebus aethiops D (2) dopamine receptor | in vitro E.coli expression system |
DRD2 Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP350184EQV1 CSB-EP350184EQV1 CSB-BP350184EQV1 CSB-MP350184EQV1 CSB-EP350184EQV1-B |
Recombinant Pan troglodytes D (2) dopamine receptor, partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF350184EQV | Recombinant Pan troglodytes D (2) dopamine receptor | in vitro E.coli expression system |
DRD2 Proteins for Meleagris gallopavo (Common turkey)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP529149MQV1 CSB-EP529149MQV1 CSB-BP529149MQV1 CSB-MP529149MQV1 CSB-EP529149MQV1-B |
Recombinant Meleagris gallopavo D (2) dopamine receptor, partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF529149MQV | Recombinant Meleagris gallopavo D (2) dopamine receptor | in vitro E.coli expression system |
DRD2 Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP740886MOH1 CSB-EP740886MOH1 CSB-BP740886MOH1 CSB-MP740886MOH1 CSB-EP740886MOH1-B |
Recombinant Mustela putorius furo D (2) dopamine receptor (DRD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF740886MOH | Recombinant Mustela putorius furo D (2) dopamine receptor (DRD2) | in vitro E.coli expression system |
DRD2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP861933DO1 CSB-EP861933DO1 CSB-BP861933DO1 CSB-MP861933DO1 CSB-EP861933DO1-B |
Recombinant Dog D (2) dopamine receptor (DRD2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF861933DO | Recombinant Dog D (2) dopamine receptor (DRD2) | in vitro E.coli expression system |
