CTSL

CTSL，即組織蛋白酶L，別名CatL、Ctsl1，是一種由人類基因編碼的溶酶體半胱氨酸蛋白酶，屬于木瓜蛋白酶家族中的成員。CTSL主要在動物各種組織細胞的溶酶體內(nèi)以酶原形式廣泛存在，其相對分子量約為30000。CTSL的作用機制涉及其在酸性環(huán)境下的活化，通過水解多種蛋白質(zhì)底物，包括激素原的激活、體內(nèi)抗原呈遞、組織器官發(fā)育等多個生理過程。CTSL在維持動物正常生命活動中扮演著重要角色，對于指導(dǎo)蛋白質(zhì)的合成與分解、T細胞分選等具有重要的生物學(xué)意義。在病理狀態(tài)下，CTSL的異常活化與腫瘤的浸潤和轉(zhuǎn)移、毛囊的形態(tài)發(fā)育及心肌病有關(guān)。CTSL還參與炎癥、血管以及細胞外基質(zhì)重建過程，其在腫瘤轉(zhuǎn)移和化療耐藥性中也扮演重要角色。

熱銷產(chǎn)品

CTSL Recombinant Monoclonal Antibody (CSB-RA006193MA1HU)

驗證數(shù)據(jù)

IHC image of CSB-RA006193MA1HU diluted at 1:30 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.

IHC image of CSB-RA006193MA1HU diluted at 1:30 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.

Immunofluorescence staining of NIH/3T3 cell with CSB-RA006193MA1HU at 1:10, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

CTSL Antibody (CSB-PA11499A0Rb)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA11499A0Rb at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA11499A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

CTSL Antibody

CTSL Protein

CTSL ELISA Kit

CTSL Antibodies

CTSL for Chlorocebus aethiops

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA006193LA01DSU	CTSL Antibody	Chlorocebus aethiops, Human	ELISA, WB

CTSL for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA000034	Cleaved-CTSL (T288) Antibody	Human	WB, ELISA
CSB-PA004835	CTSL Antibody	Human	WB, ELISA
CSB-PA996311	CTSL Antibody	Human	ELISA,IHC
CSB-PA092272	CTSL Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA11499A0Rb	CTSL Antibody	Human	ELISA, IHC, IF
CSB-RA006193MA1HU	CTSL Recombinant Monoclonal Antibody	Human	ELISA, IHC, IF

CTSL Proteins

CTSL Proteins for Felis catus (Cat) (Felis silvestris catus)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193CA CSB-EP006193CA CSB-BP006193CA CSB-MP006193CA CSB-EP006193CA-B	Recombinant Cat Cathepsin L1 (CTSL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSL Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193BO CSB-EP006193BO CSB-BP006193BO CSB-MP006193BO CSB-EP006193BO-B	Recombinant Bovine Cathepsin L1 (CTSL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSL Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193MO CSB-BP006193MO CSB-MP006193MO CSB-EP006193MO-B	Recombinant Mouse Cathepsin L1 (Ctsl1), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006193MO	Recombinant Mouse Cathepsin L1 (Ctsl1), partial	E.coli

CTSL Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193RA CSB-EP006193RA CSB-BP006193RA CSB-MP006193RA CSB-EP006193RA-B	Recombinant Rat Procathepsin L (Ctsl), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSL Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193HU CSB-EP006193HU CSB-BP006193HU CSB-MP006193HU CSB-EP006193HU-B	Recombinant Human Cathepsin L1 (CTSL1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSL Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193CH CSB-EP006193CH CSB-BP006193CH CSB-MP006193CH CSB-EP006193CH-B	Recombinant Chicken Cathepsin L1 (CTSL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSL Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193DSU CSB-BP006193DSU CSB-MP006193DSU CSB-EP006193DSU-B	Recombinant Chlorocebus aethiops Cathepsin L1 (CTSL1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006193DSU	Recombinant Chlorocebus aethiops Cathepsin L1 (CTSL1), partial	E.coli

CTSL Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193DO CSB-EP006193DO CSB-BP006193DO CSB-MP006193DO CSB-EP006193DO-B	Recombinant Dog Cathepsin L1 (CTSL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSL Proteins for Ovis aries (Sheep)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193SH CSB-EP006193SH CSB-BP006193SH CSB-MP006193SH CSB-EP006193SH-B	Recombinant Sheep Cathepsin L1 (CTSL)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSL Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006193PI CSB-EP006193PI CSB-BP006193PI CSB-MP006193PI CSB-EP006193PI-B	Recombinant Pig Cathepsin L1 (CTSL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli