CPN1
羧肽酶N亞基1（CPN1）是一種存在于血漿中的金屬蛋白酶，能夠從肽和蛋白質(zhì)的C末端切割堿性氨基酸。它也被稱(chēng)為激肽酶1和過(guò)敏毒素滅活劑。CPN1在調(diào)節(jié)激肽和過(guò)敏毒素等肽方面發(fā)揮著重要作用。此外，它還參與補(bǔ)體系統(tǒng)的調(diào)節(jié)，通過(guò)切割C3a和C5a等補(bǔ)體成分來(lái)減少補(bǔ)體介導(dǎo)的炎癥。
CPN1的常見(jiàn)別名包括CPN、SCPN、ACBP等。近年來(lái)，研究人員致力于開(kāi)發(fā)基于CPN1的藥物，用于治療與補(bǔ)體失調(diào)相關(guān)的疾病，例如自身免疫性疾病和炎癥性疾病。例如，一些研究機(jī)構(gòu)正在開(kāi)發(fā)CPN1變體和融合構(gòu)建體，以提高其活性、穩(wěn)定性和對(duì)特定底物的親和力。這些藥物有望成為治療補(bǔ)體介導(dǎo)的疾病的新型有效手段。
熱銷(xiāo)產(chǎn)品
Recombinant Human Cytochrome P450 11B1, mitochondrial (CYP11B1) (CSB-EP006390HUc7)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CYP11B1 Antibody (CSB-PA006390LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Mouse heart tissue, Mouse kidney tissue
All lanes: CYP11B1 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 58, 50 kDa
Observed band size: 58 kDa
CPN1 Antibodies
CPN1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA005156 | CYP11B1 Antibody | Human | WB, ELISA |
| CSB-PA591028 | CYP11B1 Antibody | Human | ELISA,IHC |
| CSB-PA248001 | CYP11B1 Antibody | Human | ELISA,IHC |
| CSB-PA006390LA01HU | CYP11B1 Antibody | Human, Mouse | ELISA, WB |
| CSB-PA006390LD01HU | CYP11B1 Antibody, Biotin conjugated | Human | ELISA |
CPN1 Proteins
CPN1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP006390HU CSB-BP006390HU CSB-MP006390HU CSB-EP006390HU-B |
Recombinant Human Cytochrome P450 11B1, mitochondrial (CYP11B1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006390HU | Recombinant Human Cytochrome P450 11B1, mitochondrial (CYP11B1) | E.coli |
| CSB-EP006390HUc7 | Recombinant Human Cytochrome P450 11B1, mitochondrial (CYP11B1) | E.coli |
| CSB-EP006390HUd7 | Recombinant Human Cytochrome P450 11B1, mitochondrial (CYP11B1) | E.coli |
