CCL17

CCL17，全稱為C-C motif chemokine ligand 17，也被稱為胸腺活化調節趨化因子（TARC），是CC趨化因子家族中的一員。它在人體內主要表達于胸腺，并在植物血凝素（PHA）刺激的外周血單個核細胞中瞬時表達。CCL17通過與T細胞表面的CCR4受體結合，在免疫細胞的遷移、激活和炎癥反應的調節中發揮重要作用。研究發現，CCL17在多種炎癥和免疫相關疾病中發揮作用，如哮喘、骨關節炎、多發性骨髓瘤等。針對CCL17及其受體的藥物研發已取得一定進展，例如阻斷CCL17可減輕小鼠膝骨關節炎疼痛和關節損傷，提示其在疾病治療中的潛在應用價值。

熱銷產品

Recombinant Human C-C motif chemokine 17 (CCL17) (Active) (CSB-MP856406HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Anti-CCL17 recombinant antibody (CSB-RA856406MA1HU) at 2 μg/ml can bind Human CCL17 protein. The EC₅₀ is 2.403-2.741 ng/mL.

CCL17 Recombinant Monoclonal Antibody (CSB-RA856406MA1HU)

驗證數據

The Binding Activity of Human CCL17 with Anti-CCL17 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-CCL17 recombinant antibody at 2 μg/mL can bind Human CCL17 protein (CSB-MP856406HU) . The EC₅₀ is 2.403-2.741 ng/mL.

The Binding Activity of Macaca mulatta CCL17 with Anti-CCL17 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-CCL17 recombinant antibody at 2 μg/mL can bind Mouse Ccl17 protein (CSB-MP6512MO). The EC₅₀ is 0.9792-1.486 ng/mL.

The Binding Activity of Macaca mulatta CCL17 with Anti-CCL17 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-CCL17 recombinant antibody at 2 μg/mL can bind Macaca mulatta CCL17 protein (CSB-MP811562MOW). The EC₅₀ is 1.953-2.469 ng/mL.

Overlay Peak curve showing Raji cells stained with CSB-RA856406MA1HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10⁶cells) for 45min at 4℃. The secondary antibody used was Fluorescein (FITC) AffiniPure Goat Anti-Human IgG, Fcγ fragment specific at 1:200 dilution for 35 min at 4℃.Control antibody (green line) was human IgG1 (1ug/1*10⁶cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human thymus activation regulated chemokine,TARC ELISA Kit (CSB-E09257h)

驗證數據

貨號：CSB-E09257h

規格：96T/48T

靈敏度：3.9 pg/mL

檢測范圍：15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CCL17 Antibody

CCL17 Protein

CCL17 ELISA Kit

CCL17 Antibodies

CCL17 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA113746	CCL17 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA174494	CCL17 Antibody	Human	ELISA,WB,IHC
CSB-PA856406LA01HU	CCL17 Antibody	Human	ELISA, IHC
CSB-PA856406LB01HU	CCL17 Antibody, HRP conjugated	Human	ELISA
CSB-PA856406LC01HU	CCL17 Antibody, FITC conjugated	Human
CSB-PA856406LD01HU	CCL17 Antibody, Biotin conjugated	Human	ELISA
CSB-RA856406MA1HU	CCL17 Recombinant Monoclonal Antibody	Human, Mouse, Macaca fascicularis	ELISA, FC

CCL17 Proteins

CCL17 Proteins for Macaca mulatta (Rhesus macaque)

產品貨號	產品名稱	來源
CSB-YP811562MOW CSB-EP811562MOW CSB-BP811562MOW CSB-EP811562MOW-B	Recombinant Macaca mulatta C-C motif chemokine 17 (CCL17)	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli

CCL17 Proteins for Felis catus (Cat) (Felis silvestris catus)

產品貨號	產品名稱	來源
CSB-YP815510CA CSB-EP815510CA CSB-BP815510CA CSB-MP815510CA CSB-EP815510CA-B	Recombinant Cat C-C motif chemokine 17 (CCL17)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCL17 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP856406HU CSB-EP856406HU CSB-BP856406HU	Recombinant Human C-C motif chemokine 17 (CCL17)	Yeast E.coli Baculovirus
CSB-AP000611HU	Recombinant Human C-C motif chemokine 17 protein (CCL17)	E.Coli
CSB-MP856406HU	Recombinant Human C-C motif chemokine 17 (CCL17) (Active)	Mammalian cell
CSB-EP856406HU-B	Recombinant Human C-C motif chemokine 17 (CCL17), Biotinylated	E.coli