C9orf72
C9orf72基因位于人體染色體上，編碼的蛋白質(zhì)在細(xì)胞內(nèi)具有多種重要功能。它定位于細(xì)胞核中，調(diào)控DNA修復(fù)過(guò)程，與非同源末端修復(fù)途徑的核心蛋白結(jié)合，促進(jìn)DNA損傷的修復(fù)。此外，C9orf72還能與SMCR8和WDR41形成復(fù)合體，調(diào)節(jié)自噬過(guò)程，維持細(xì)胞內(nèi)的蛋白質(zhì)穩(wěn)態(tài)。然而，當(dāng)C9orf72基因發(fā)生突變時(shí)，如核酸重復(fù)序列的過(guò)度擴(kuò)張，會(huì)導(dǎo)致神經(jīng)退行性疾病的發(fā)生。這種突變不僅影響基因的正常表達(dá)，還可能導(dǎo)致蛋白質(zhì)功能紊亂。
熱銷(xiāo)產(chǎn)品
Human Uncharacterized protein C9orf72(C9orf72) ELISA kit
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL004345HU
規(guī)格：96T/48T
靈敏度：7.8 pg/mL
檢測(cè)范圍：31.25 pg/mL-2000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
C9orf72 Antibodies
C9orf72 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA842710LA01HU | C9orf72 Antibody | Human | ELISA, IHC, IF |
| CSB-PA842710LC01HU | C9orf72 Antibody, FITC conjugated | Human |
C9orf72 Proteins
C9orf72 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP842710HU CSB-EP842710HU CSB-BP842710HU CSB-MP842710HU CSB-EP842710HU-B |
Recombinant Human Guanine nucleotide exchange factor C9orf72 (C9orf72) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
C9orf72 ELISA Kit
C9orf72 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-EL004345HU | Human Uncharacterized protein C9orf72(C9orf72) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 7.8 pg/mL |
