BLNK
B-cell linker protein is a protein in humans that is encoded by BLNK gene. Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
BLNK Antibodies
BLNK for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA002717GA01HU | BLNK Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA598542 | Phospho-BLNK (Tyr96) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA246025 | Phospho-BLNK (Tyr84) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA000998 | BLNK Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA009047 | Phospho-BLNK (Y96) Antibody | Human,Mouse,Monkey | WB, IHC, ELISA |
| CSB-PA009048 | Phospho-BLNK (Y84) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA195809 | BLNK Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA958582 | BLNK Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA840984LA01HU | BLNK Antibody | Human | ELISA, WB, IHC, IF |
BLNK Proteins
BLNK Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP679872RA CSB-EP679872RA CSB-BP679872RA CSB-MP679872RA CSB-EP679872RA-B |
Recombinant Rat B-cell linker protein (Blnk) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BLNK Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP840984HU CSB-EP840984HU CSB-BP840984HU CSB-MP840984HU CSB-EP840984HU-B |
Recombinant Human B-cell linker protein (BLNK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BLNK Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP879429MO CSB-EP879429MO CSB-BP879429MO CSB-MP879429MO CSB-EP879429MO-B |
Recombinant Mouse B-cell linker protein (Blnk) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BLNK Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP896856CH CSB-EP896856CH CSB-BP896856CH CSB-MP896856CH CSB-EP896856CH-B |
Recombinant Chicken B-cell linker protein (BLNK), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
