BABAM2
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX . In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Within the BRISC complex, acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
BABAM2 Antibodies
BABAM2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002808GA01HU | BRE Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA080030 | BRE Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA047722 | BRE Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA298431 | BRE Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA873684LA01HU | BABAM2 Antibody | Human | ELISA, IHC, IF |
BABAM2 Proteins
BABAM2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002808BO CSB-EP002808BO CSB-BP002808BO CSB-MP002808BO CSB-EP002808BO-B |
Recombinant Bovine BRCA1-A complex subunit BRE (BRE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Branchiostoma floridae (Florida lancelet) (Amphioxus)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002808BVY CSB-EP002808BVY CSB-BP002808BVY CSB-MP002808BVY CSB-EP002808BVY-B |
Recombinant Branchiostoma floridae BRCA1-A complex subunit BRE (BRE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP704077DIL CSB-EP704077DIL CSB-BP704077DIL CSB-MP704077DIL CSB-EP704077DIL-B |
Recombinant Danio rerio BRCA1-A complex subunit BRE (bre) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP713020PYX CSB-EP713020PYX CSB-BP713020PYX CSB-MP713020PYX CSB-EP713020PYX-B |
Recombinant Pongo abelii BRCA1-A complex subunit BRE (BRE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP715694XBF CSB-EP715694XBF CSB-BP715694XBF CSB-MP715694XBF CSB-EP715694XBF-B |
Recombinant Xenopus tropicalis BRCA1-A complex subunit BRE (bre) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP723207CH CSB-EP723207CH CSB-BP723207CH CSB-MP723207CH CSB-EP723207CH-B |
Recombinant Chicken BRCA1-A complex subunit BRE (BRE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Mesocricetus auratus (Golden hamster)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP740868MRG CSB-EP740868MRG CSB-BP740868MRG CSB-MP740868MRG CSB-EP740868MRG-B |
Recombinant Mesocricetus auratus BRCA1-A complex subunit BRE (Bre) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP757591RA CSB-EP757591RA CSB-BP757591RA CSB-MP757591RA CSB-EP757591RA-B |
Recombinant Rat BRCA1-A complex subunit BRE (Bre) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP764112XBE CSB-EP764112XBE CSB-BP764112XBE CSB-MP764112XBE CSB-EP764112XBE-B |
Recombinant Xenopus laevis BRCA1-A complex subunit BRE (bre) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP815673MO CSB-EP815673MO CSB-BP815673MO CSB-MP815673MO CSB-EP815673MO-B |
Recombinant Mouse BRCA1-A complex subunit BRE (Bre) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Saguinus oedipus (Cotton-top tamarin)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP837834SWB CSB-EP837834SWB CSB-BP837834SWB CSB-MP837834SWB CSB-EP837834SWB-B |
Recombinant Saguinus oedipus BRCA1-A complex subunit BRE (BRE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP851945DSU CSB-EP851945DSU CSB-BP851945DSU CSB-MP851945DSU CSB-EP851945DSU-B |
Recombinant Chlorocebus aethiops BRCA1-A complex subunit BRE (BRE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BABAM2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP873684HU CSB-EP873684HU CSB-BP873684HU CSB-MP873684HU CSB-EP873684HU-B |
Recombinant Human BRCA1-A complex subunit BRE (BRE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
