ARRB2
Beta-arrestin-2 is a protein in humans that is encoded by ARRB2 gene. Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and recruiting the GPRCs to the adapter protein 2 complex 2 (AP-2) in clathrin-coated pits (CCPs).
ARRB2 Antibodies
ARRB2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002135GA01HU | ARRB2 Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA002135LA01HU | ARRB2 Antibody | Human, Rat | ELISA, WB, IHC, IF |
ARRB2 Proteins
ARRB2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP002135BO CSB-BP002135BO CSB-MP002135BO CSB-EP002135BO-B |
Recombinant Bovine Beta-arrestin-2 (ARRB2) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ARRB2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002135HU1 CSB-EP002135HU1 CSB-BP002135HU1 CSB-MP002135HU1 CSB-EP002135HU1-B |
Recombinant Human Beta-arrestin-2 (ARRB2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ARRB2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002135RA CSB-EP002135RA CSB-BP002135RA CSB-MP002135RA CSB-EP002135RA-B |
Recombinant Rat Beta-arrestin-2 (Arrb2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ARRB2 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP729058PYX CSB-EP729058PYX CSB-BP729058PYX CSB-MP729058PYX CSB-EP729058PYX-B |
Recombinant Pongo abelii Beta-arrestin-2 (ARRB2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ARRB2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP835595MO CSB-EP835595MO CSB-BP835595MO CSB-MP835595MO CSB-EP835595MO-B |
Recombinant Mouse Beta-arrestin-2 (Arrb2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ARRB2 ELISA Kit
ARRB2 ELISA Kit for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL002135RA | Rat Beta-arrestin-2(ARRB2) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 11.72 pg/mL |
