ANGPTL4
ANGPTL4，全稱為血管生成素樣蛋白4，是一種多功能分泌蛋白，在調(diào)節(jié)葡萄糖穩(wěn)態(tài)、脂質(zhì)代謝和胰島素敏感性方面發(fā)揮著重要作用。別名包括ANGPTL4、血管生成素相關(guān)蛋白4、NL2、ARP4、FIAF、HARP、PGAR、HFARP、TGQTL和UNQ171。ANGPTL4通過滅活脂蛋白脂肪酶（LPL）來控制血液中甘油三酯的清除，從而調(diào)節(jié)脂質(zhì)代謝。此外，ANGPTL4還參與炎癥反應(yīng)和血管生成過程。研究表明，ANGPTL4的過表達(dá)與類風(fēng)濕關(guān)節(jié)炎的發(fā)病相關(guān)，其過表達(dá)水平與疾病的嚴(yán)重程度呈正相關(guān)。最近，中國科學(xué)院深圳先進(jìn)技術(shù)研究院的研究發(fā)現(xiàn)，ANGPTL4能夠抑制鐵死亡介導(dǎo)肺癌的輻射抗性，為肺癌的治療提供了新的思路。目前，ANGPTL4已成為多個(gè)疾病研究和藥物研發(fā)的重要靶點(diǎn)，相關(guān)藥物研發(fā)進(jìn)展也備受關(guān)注。
熱銷產(chǎn)品
Recombinant Human Angiopoietin-related protein 4 (ANGPTL4), partial (CSB-EP866314HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP101444h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ANGPTL4.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP101444h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ANGPTL4.
ANGPTL4 Antibody (CSB-PA866314ESR2HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: Angiopoietin-related protein 4 antibody at 2μg/ml + Mouse heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 41, 27 kDa
Observed band size: 46 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA866314ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA866314ESR2HU at dilution of 1:100
ANGPTL4 Antibodies
ANGPTL4 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001712GA01HU | ANGPTL4 Antibody | Human | ELISA,IHC |
| CSB-PA866314ESR1HU | ANGPTL4 Antibody | Human | ELISA, IHC |
| CSB-PA866314ESR2HU | ANGPTL4 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA005044 | ANGPTL4 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA261295 | ANGPTL4 Antibody | Human | ELISA,IHC |
| CSB-PA231310 | ANGPTL4 Antibody | Human | ELISA,IHC |
| CSB-PA866314EA01HU | ANGPTL4 Antibody | Human | ELISA, WB |
| CSB-PA866314EB01HU | ANGPTL4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA866314EC01HU | ANGPTL4 Antibody，F(xiàn)ITC conjugated | Human |
ANGPTL4 Proteins
ANGPTL4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP866314HU1 | Recombinant Human Angiopoietin-related protein 4 (ANGPTL4), partial | E.coli |
| CSB-YP866314HU CSB-EP866314HU CSB-BP866314HU CSB-MP866314HU CSB-EP866314HU-B |
Recombinant Human Angiopoietin-related protein 4 (ANGPTL4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANGPTL4 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP645629BO CSB-EP645629BO CSB-BP645629BO CSB-MP645629BO CSB-EP645629BO-B |
Recombinant Bovine Angiopoietin-related protein 4 (ANGPTL4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANGPTL4 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP652704PI CSB-EP652704PI CSB-BP652704PI CSB-MP652704PI CSB-EP652704PI-B |
Recombinant Pig Angiopoietin-related protein 4 (ANGPTL4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANGPTL4 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP761460RA CSB-EP761460RA CSB-BP761460RA CSB-MP761460RA CSB-EP761460RA-B |
Recombinant Rat Angiopoietin-related protein 4 (Angptl4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANGPTL4 ELISA Kit
ANGPTL4 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL001712HU | Human Angiopoietin-related protein 4(ANGPTL4) ELISA kit | serum, plasma, tissue homogenates | 0.39 ng/mL |
ANGPTL4 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL001712MO | Mouse Angiopoietin-related protein 4(ANGPTL4) ELISA kit | serum, plasma, tissue homogenates | 0.78 pg/mL |
ANGPTL4 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL001712RA | Rat Angiopoietin-related protein 4(ANGPTL4) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates, bronchoalveolar lavage fluid, urine | 1.95 pg/mL |
