CIITA
MHC class II transactivator is a protein in humans that is encoded by CIITA gene. Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. May act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Also mediates enhanced MHC class I transcription; the promoter element requirements for CIITA-mediated transcription are distinct from those of constitutive MHC class I transcription, and CIITA can functionally replace TAF1 at these genes. Exhibits intrinsic GTP-stimulated acetyltransferase activity. Exhibits serine/threonine protein kinase activity
CIITA Antibodies
CIITA for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA349864 | CIITA Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA010532 | CIITA Antibody | Human,Mouse,Rat | WB, ELISA |
CIITA Proteins
CIITA Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005435MO CSB-EP005435MO CSB-BP005435MO CSB-MP005435MO CSB-EP005435MO-B |
Recombinant Mouse MHC class II transactivator (Ciita), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CIITA Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005435HU CSB-EP005435HU CSB-BP005435HU CSB-MP005435HU CSB-EP005435HU-B |
Recombinant Human MHC class II transactivator (CIITA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
