Recombinant Rat Sulfhydryl oxidase 1 (Qsox1)

in vitro E.coli expression system

中文名稱：

大鼠Qsox1重組蛋白
貨號：

CSB-CF750354RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

Qsox1
Uniprot No.：

Q6IUU3
別名：

Qsox1; Qscn6; Sox2; Sulfhydryl oxidase 1; rQSOX; rSOx; FAD-dependent sulfhydryl oxidase-2; SOx-2; Quiescin Q6
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

33-750
氨基酸序列

ARLSVLYSSSDPLTLLDADTVRPAVLGSSSAWAVEFFASWCGHCIAFAPTWKELANDVKD WRPALNLAVLDCADETNSAVCREFNIAGFPTVRFFKAFSKNGTGTALPAAGANVQTLRMR LIDALESHRDTWPPACPPLEPAKLKDINEFFTRSKAEYLALIFEREDSYLGREVTLDLSQ FHAVAVRRVLNSESDVVSKFAVTDFPSCYLLLRNGSVSRVPVLVESRPFYTSYLRGLPGL TREAPPTTAAPVTPDKIAPTVWKFADRSKIYMADLESALHYILRVEVGKFSVLEGQRLVA LKKFVAVLAKYFPGQPLVQNFLHSINDWLQKQQKKKIPYSYFKAALDSRKENAVLAEKVN WIGCQGSEPHFRGFPCSLWVLFHFLTVQAHRYSEAHPQEPADGQEVLQAMRSYVQSFFGC RDCANHFEQMAAASMHQVKSPSNAVLWLWTSHNRVNARLSGALSEDPQFPKVQWPPRELC SACHNEVNGQVPLWDLGATLNFLKAHFSPANIVRDPPAPGPASRRGTQDPEASPNLVMDT LKLETGNSVLGHEQAASAASPGATALDVPAGKPEASGPQELNAGLSMGGASPGQGPPEHT EELLRDVQENAQGQQHLSKRDTEALLLPEVNHLQGPLAPRRGGHSPKQLASILEGEPEAL AIQGRRQWLQVLGGGVSFLDISLCVGLYSVSFMGLLAMYTYFRARMRTPKGHVSYPTA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.
基因功能參考文獻：
1. QSOX1 induces VSMC migration and proliferation in vitro and contributes to neointima thickening in balloon-injured rat carotids. PMID: 25766108
2. RnQSOX1 gives unprecedented insight into the functional group of the cysteine involved in dithiol/disulfide exchange and provides the framework for analysis of the energetics of electron transfer in the flavin adenine dinucleotide cofactor. PMID: 24888638
3. At least two transcripts were detected in brain, suggesting a tissue-specific splicing of its mRNA. PMID: 12438924
4. The molecular cloning of a new putative brain sulfhydryl oxidase cDNA, rQSOX-L, was reported. PMID: 16806532
5. The kinetics of QSOX1 expression suggest a more protective effect of QSOX1 rather than an involvement of this protein in apoptosis PMID: 17927979
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亞細胞定位：

[Isoform 1]: Golgi apparatus membrane; Single-pass membrane protein. Secreted.; [Isoform 3]: Secreted.
蛋白家族：

Quiescin-sulfhydryl oxidase (QSOX) family
組織特異性：

Isoform 3: Detected in seminal vesicle fluid (at protein level). Isoform 1: Detected in brain, hypophysis, heart, testis and the seminal vesicle. Isoform 3: Highly expressed in the seminal vesicles followed by testis, heart, brain, thymus, hypophysis and
數(shù)據(jù)庫鏈接：

KEGG: rno:84491

STRING: 10116.ENSRNOP00000005052

UniGene: Rn.44920