Recombinant Mouse Mitochondrial inner membrane protease subunit 2 (Immp2l)

in vitro E.coli expression system

中文名稱：

小鼠Immp2l重組蛋白
貨號：

CSB-CF806416MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

Immp2l
Uniprot No.：

Q8BPT6
別名：

Immp2l; Mitochondrial inner membrane protease subunit 2; IMP2-like protein
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區(qū)域：

1-175
氨基酸序列

MAQSQSWARRCFKAFCKGFFVAVPVAVTFLDRVACVARVEGSSMQPSLNPGGSQSSDVVL LNHWKVRNFEVQRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRLVKVPRGHMWV EGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQRLESVLPPERCPLQTGEK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
基因功能參考文獻：
1. The results indicate that IMP2 deficiency delayed bone remodeling by significantly inhibiting the activity of osteoclasts and impairing their adhesion. PMID: 29322325
2. data suggest that respiratory deficiency is not the cause of the observed Immp2l mutant phenotypes. PMID: 25460737
3. provides evidence for a causal role of oxidative stress in neurodegeneration of Immp2l mutant mice PMID: 26616244
4. IMP2 as a developmental stage-dependent regulator of the differentiation potentials of NPCs in the mouse neocortex. PMID: 23331702
5. This study demomistrated that Immp2l deficiency increases ischemic brain damage by enhancing O(2)(-) production and damaging mitochondrial functional performance. PMID: 21824519
6. Mitochondrial peptidase IMMP2L mutation causes early onset of age-associated disorders and impairs adult stem cell self-renewal PMID: 21332923
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亞細胞定位：

Mitochondrion inner membrane; Single-pass membrane protein.
蛋白家族：

Peptidase S26 family, IMP2 subfamily
數(shù)據(jù)庫鏈接：

KEGG: mmu:93757

STRING: 10090.ENSMUSP00000116441

UniGene: Mm.363813