Recombinant Human Mas-related G-protein coupled receptor member X3

中文名稱：

人MRGPRX3重組蛋白
貨號：

CSB-CF850382HU
說明書：

MSDS Datasheet
規格：
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

MRGPRX3
Uniprot No.：

Q96LB0
別名：

G protein coupled receptor SNSR1; G protein coupled receptor SNSR2; G protein-coupled receptor MRGX 3; G protein-coupled receptor MRGX3 ; GPCR; Mas related GPCR member X3; Mas-related G protein coupled MRGX 3; Mas-related G protein coupled MRGX3; Mas-related G-protein coupled receptor member X3; MAS-related GPR, member X3; MRGPRX3; MRGX3; MRGX3_HUMAN; Sensory neuron-specific G-protein coupled receptor 1; Sensory neuron-specific G-protein coupled receptor 1/2; SNSR1; SNSR2
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length
來源：

in vitro E.coli expression system
蛋白標簽：

N-terminal His-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.
基因功能參考文獻：
1. Our data demonstrate that GPR182 is an endothelial subtype-specific marker for human sinusoidal EC of the liver, spleen, lymph node and bone marrow. In addition, we provide evidence for GPR182-dependent downstream signaling via ERK and SRF pathways that may be involved in regulating endothelial subtype-specific sinusoidal differentiation and sinusoidal functions such as permeability. PMID: 29408502
2. Potential of GPCRs to modulate MAPK and mTOR pathways in different stages of the neurodegenerative disease. PMID: 28189739
3. overexpression of the human MrgX3 gene causes a disturbance of the normal cell-differentiation process PMID: 15809047
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family, Mas subfamily
組織特異性：

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
數據庫鏈接：

HGNC: 17980

OMIM: 607229

KEGG: hsa:117195

STRING: 9606.ENSP00000379571

UniGene: Hs.380177