Recombinant Danio rerio Calcium release-activated calcium channel protein 1 (orai1)

in vitro E.coli expression system

中文名稱：

斑馬魚orai1重組蛋白
貨號：

CSB-CF761459DIL
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

orai1
Uniprot No.：

Q6TLE6
別名：

orai1; tmem142a; zgc:109721; Calcium release-activated calcium channel protein 1; Protein orai-1; Transmembrane protein 142A
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

full length protein
表達區域：

1-222
氨基酸序列

MKMSRSEHSLQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDTNHDYPPGLLI AFSACTTVLVAVHLFALMVSTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTV IGTLLFLAGVVLLCWVKFLPIKPKGQKNGTVSAGVAAAITSTSIMVPFGLVFIVFAVHFY RSLVSHKTDRQFQELEELEDLQNELDHREEVSTLQSPGSLYP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores.
基因功能參考文獻：
1. Orai1 is localized to the cleavage furrow during cytokinesis of the first and second cell division cycles in zebrafish embryos. PMID: 27702423
2. The findings identify ORAI1 as an important regulator of cardiac and skeletal muscle function and provide evidence linking ORAI1-mediated calcium signaling to sarcomere integrity and cardiomyocyte function. PMID: 22302996
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Orai family
數據庫鏈接：

KEGG: dre:402892

STRING: 7955.ENSDARP00000022726

UniGene: Dr.85339