Recombinant Australian bat lyssavirus Glycoprotein G (G)

in vitro E.coli expression system

中文名稱：

Recombinant Australian bat lyssavirus Glycoprotein G(G)
貨號：

CSB-CF889536AKAU
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

G
Uniprot No.：

Q9QSP1
別名：

G; Glycoprotein
種屬：

Australian bat lyssavirus (isolate Bat/AUS/1996) (ABLV)
蛋白長度：

Full Length of Mature Protein
表達(dá)區(qū)域：

20-525
氨基酸序列

QFPLYAIPDKLGPWSPIDIHHLSCPNNLIVEDEGCTSLSGFSYMELKVGFITTIKVSGFT CTGVVTESETYTNFFGYVTTTFKRKHFRPTPESCRKAYNWKIAGDPRYEESLHNPYPDYH WLRTVTTTKESLLIISPSVVDMDPYDKSLHSRMFPKGSCSGASIPSVFCSTNHDYTLWMP EDSNSGMSCDIFTMSKGKKASKGGKVCGFVDERGLYKSLKGACKLKLCGISGLRLLDGSW VSIQNHEEVKWCSPNQLVNIHDFNADEIEHLIVEELIKEREECLDALESIITTKSVSFRR LSHLRKLVPGFGKAYTIINKTLMEADAHYKSVRTWDEIIPSKGCLKVREKCHPPYNGVFF NGIILGPDGQVLIPEMQSSLLHQHTELLESSVIPLIHPLADPSTIFRGDDEAEGFIEVHL PDIQKQVSGIDLGLSEWERYLIIGISAIILFILAIIFTICCRRCKRRKKIRTDHIELDRK VSVTSQSGKSIPSWESYKSRQGHSRS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
基因功能參考文獻(xiàn)：
1. The predominant pathway mediated by Australian bat lyssavirus G envelope for internalization into HEK293T cells is clathrin-and actin-dependent also requiring Rab5. PMID: 24576301
亞細(xì)胞定位：

Virion membrane; Single-pass type I membrane protein.
蛋白家族：

Lyssavirus glycoprotein family
數(shù)據(jù)庫鏈接：

KEGG: vg:926730