Recombinant Xenopus laevis Iroquois-class homeodomain protein irx-3 (irx3)

中文名稱：

有爪蟾蜍irx3重組蛋白
貨號：

CSB-YP011835XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍irx3重組蛋白
貨號：

CSB-EP011835XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍irx3重組蛋白
貨號：

CSB-EP011835XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍irx3重組蛋白
貨號：

CSB-BP011835XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍irx3重組蛋白
貨號：

CSB-MP011835XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

irx3
Uniprot No.：

O42261
別名：

irx3; iro3Iroquois-class homeodomain protein irx-3; Iroquois homeobox protein 3; Xiro3
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區域：

1-448
氨基酸序列

MSFPQLGYQY IRPLYPSDRQ SVGVTRSGTE LSPAGTLSNV LSSVYGAPYA AAAAAQAYGA FLPYSAELPI FPQLGSQYDM KDSPGVQHAA FSHPHPAFYP YGQYQFGDPS RPKNATREST STLKAWLNEH RKNPYPTKGE KIMLAIITKM TLTQVSTWFA NARRRLKKEN KMTWAPRSRT DEEGNAYGSD HEEDKHEDEE EIDLENIDTE DIESKEDLDD PDTDIHSDSK TDTRSDSEVS DGFEDLNVPE DRLLKSVVGQ RQLLNEEPQD KCALSSDAKV PQPACEQIKL NRLPPSPPQE NNMPVAHKPK IWSLAETATT PDNPRNSPNT GGSVNTQNLI AQHRLIASPG SRFQGWTGRA FSAQQLSLLN SAHFLQGLGV SHTAPCSGNA SFPKAAESKC STNSLTDRPS TVDIEKTIPV LNTAFQPVQR RSQNHLDAAM ILSALSSS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Both up-regulates and down-regulates gene expression during neural development. Acts early in neural plate development to induce proneural gene expression and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling. Subsequently required for proper formation of the intermediate tubule segment of the pronephros.
基因功能參考文獻：
1. Irx3 is transcriptionally induced by the Wnt/beta-catenin signaling pathway during anteroposterior patterning of the neural axis. PMID: 20979027
2. Irx3 is the first gene known to be necessary and sufficient to specify nephron segment fate in vivo. PMID: 17875669
亞細胞定位：

Nucleus.
蛋白家族：

TALE/IRO homeobox family
組織特異性：

Primarily expressed in the developing central nervous system (CNS). At gastrula stage, expressed in both the superficial and deep layers of the presumptive neural plate with expression spreading to the prospective hindbrain, spinal cord and midbrain-hindb
數據庫鏈接：

KEGG: xla:399365

UniGene: Xl.4522