Recombinant Saccharomyces cerevisiae Protein phosphatase 2C homolog 1 (PTC1)

中文名稱：

釀酒酵母PTC1重組蛋白
貨號：

CSB-YP333978SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母PTC1重組蛋白
貨號：

CSB-EP333978SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母PTC1重組蛋白
貨號：

CSB-EP333978SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母PTC1重組蛋白
貨號：

CSB-BP333978SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母PTC1重組蛋白
貨號：

CSB-MP333978SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PTC1
Uniprot No.：

P35182
別名：

PTC1; TPD1; YDL006W; D2925; Protein phosphatase 2C homolog 1; PP2C-1; EC 3.1.3.16
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-281
氨基酸序列

MSNHSEILER PETPYDITYR VGVAENKNSK FRRTMEDVHT YVKNFASRLD WGYFAVFDGH AGIQASKWCG KHLHTIIEQN ILADETRDVR DVLNDSFLAI DEEINTKLVG NSGCTAAVCV LRWELPDSVS DDSMDLAQHQ RKLYTANVGD SRIVLFRNGN SIRLTYDHKA SDTLEMQRVE QAGGLIMKSR VNGMLAVTRS LGDKFFDSLV VGSPFTTSVE ITSEDKFLIL ACDGLWDVID DQDACELIKD ITEPNEAAKV LVRYALENGT TDNVTVMVVF L
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

It has a serine and a weak tyrosine phosphatase activity with ratios of serine to tyrosine phosphatase activity as high as 200:1. It is essential for growth or germination at 37 degrees Celsius. May have a role in the heat shock response. Involved in tRNA splicing and cell separation.
基因功能參考文獻：
1. Data show that Ptc1 is required for proper G2-M cell cycle transition after activation of the cell wall integrity pathway. PMID: 27169355
2. biochemical and genetic evidence that Mkk1 transmits most of the signaling through the CWI pathway and that Ptc1 directly downregulates the CWI pathway at the level of the MAPKKs PMID: 26546002
3. Ptc1 has overlapping functions with Reg1-Glc7 and Sit4 in glucose regulation of SNF1/AMPK and cell viability. PMID: 24019512
4. Ptc1p regulates Mmr1p phosphorylation, localization, and function. PMID: 22119524
5. Nbp2 serves as the network hub and brings seven kinases in close contact to Ptc1. PMID: 21118957
6. Expression profiling of the 6 protein phosphatase 2C family and the effects of mutation of the Ptc1 gene on gene expression and phenotype are reported PMID: 16973600
7. These findings indicate that Ptc1p and Nbp2p regulate endoplasmic reticulum inheritance through the cell wall integrity (CWI) mitogen-activated protein kinase (MAPK) pathway by modulating the MAPK, Slt2p. PMID: 16977319
8. PTC1 promotes the association of myosin-V with its organelle-specific adaptor proteins. PMID: 19116310
9. Results show that Ptc1, a type 2C protein phosphatase, is required for the normal functioning of the TOR pathway. PMID: 19273591
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蛋白家族：

PP2C family
數據庫鏈接：

KEGG: sce:YDL006W

STRING: 4932.YDL006W