Recombinant Saccharomyces cerevisiae Phosphoinositide phosphatase SAC1 (SAC1), partial

中文名稱：

釀酒酵母SAC1重組蛋白
貨號：

CSB-YP333690SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母SAC1重組蛋白
貨號：

CSB-EP333690SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母SAC1重組蛋白
貨號：

CSB-EP333690SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母SAC1重組蛋白
貨號：

CSB-BP333690SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母SAC1重組蛋白
貨號：

CSB-MP333690SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SAC1
Uniprot No.：

P32368
別名：

SAC1; RSD1; YKL212W; Phosphoinositide phosphatase SAC1; EC 3.1.3.-; Recessive suppressor of secretory defect
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P). Has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2). May be involved in the coordination of the activities of the secretory pathway and the actin cytoskeleton.
基因功能參考文獻：
1. this study showed that the PI4P-phosphatase Sac1p, by maintaining a PI4P gradient at the endoplasmic reticulum / plasma membrane interface, drove phosphatidylserine transport. PMID: 26206936
2. Collectively, these results suggested that Sac1 is involved in the maintenance of a normal rate of biosynthesis and distribution of phosphatidylserine. PMID: 24578286
3. Sac1 trafficking depends on Hog1 function. PMID: 22882253
4. Vps74 binds directly to the catalytic domain of Sac1 PMID: 22553352
5. lipid composition of the substrate membrane plays an important role in the control of Sac1 function PMID: 22452743
6. A COOH-terminal region in yeast Sac1p is crucial for ER targeting by directly interacting with dolicholphosphate mannose synthase Dpm1p. PMID: 15657391
7. analysis of growth control of Golgi phosphoinositides by reciprocal localization of sac1 lipid phosphatase and pik1 4-kinase PMID: 17908202
8. Regulation of Sac1p expression via the concentration of its major substrate PI(4)P ensures proper maintenance of compartment-specific pools of PI(4)P PMID: 18226253
9. Modulation of sphingolipid metabolism by the phosphatidylinositol-4-phosphate phosphatase Sac1p through regulation of phosphatidylinositol in Saccharomyces cerevisiae PMID: 19139096
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亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
數據庫鏈接：

KEGG: sce:YKL212W

STRING: 4932.YKL212W