Recombinant Saccharomyces cerevisiae Monopolin complex subunit LRS4 (LRS4)

中文名稱：

釀酒酵母LRS4重組蛋白
貨號：

CSB-YP311966SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母LRS4重組蛋白
貨號：

CSB-EP311966SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母LRS4重組蛋白
貨號：

CSB-EP311966SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母LRS4重組蛋白
貨號：

CSB-BP311966SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母LRS4重組蛋白
貨號：

CSB-MP311966SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LRS4
Uniprot No.：

Q04087
別名：

LRS4; YDR439W; D9461.25Monopolin complex subunit LRS4; Loss of rDNA silencing protein 4
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-347
氨基酸序列

MTTLLQLLSN YYKAKLDSER IYNEYVQSQY EFASLDKLNN NKGDPKKVVD ETLFLQRQIA QLNKQLQLSF QENEKLLSVQ KNQKALYQSK LSSKDAFIDD LKLKLKVEQI SVDKHNKERT PSTGRDEQQR NSKAAHTSKP TIHLLSPIVN RDKPNNQTND RGGNDPDSPT SQRRSRGLRS LLSSGKNTIF DSISKNLDDE INENAHIRND TTSSKIAGKS PSRLSALQKS PELRKERNNM ILKEHILRSK DDQNITSSRK LDNIELSSIG DSTAMTSRSS TVNANDILGN EENDGITKLK RVNKLTSSPV KRDCSTNKKR KLTKQRIATL PNSDEELSNN LNVDEFV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis. Involved in rDNA silencing.
基因功能參考文獻：
1. The Lrs4-Csm1 complex localize to kinetochores during anaphase and is important for ensuring accurate chromosome segregation. (LRS4 protein) PMID: 20818155
2. Csm1(Psc1)/Lrs4(Mde4) functions as a molecular clamp, crosslinking kinetochore components to enforce sister chromatid co-orientation in S. cerevisiae meiosis I and to suppress merotelic attachment in S. pombe mitosis. PMID: 20723757
亞細胞定位：

Nucleus, nucleolus. Chromosome, centromere. Note=Transiently released from the nucleolus and localized to the centromere regions during late pachytene. This relocation is CDC5 dependent.
數據庫鏈接：

KEGG: sce:YDR439W

STRING: 4932.YDR439W