Recombinant Saccharomyces cerevisiae Chromosome segregation in meiosis protein 3 (CSM3)

中文名稱：

Recombinant Saccharomyces cerevisiae Chromosome segregation in meiosis protein 3(CSM3)
貨號：

CSB-YP312018SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Chromosome segregation in meiosis protein 3(CSM3)
貨號：

CSB-EP312018SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Chromosome segregation in meiosis protein 3(CSM3)
貨號：

CSB-EP312018SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Chromosome segregation in meiosis protein 3(CSM3)
貨號：

CSB-BP312018SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Chromosome segregation in meiosis protein 3(CSM3)
貨號：

CSB-MP312018SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CSM3
Uniprot No.：

Q04659
別名：

CSM3; YMR048W; YM9796.01Chromosome segregation in meiosis protein 3
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-317
氨基酸序列

MDQDFDSLLL GFNDSDSVQK DPTVPNGLDG SVVDPTIADP TAITARKRRP QVKLTAEKLL SDKGLPYVLK NAHKRIRISS KKNSYDNLSN IIQFYQLWAH ELFPKAKFKD FMKICQTVGK TDPVLREYRV SLFRDEMGMS FDVGTRETGQ DLERQSPMVE EHVTSAEERP IVADSFAQDK RNVNNVDYDN DEDDDIYHLS YRNRRGRVLD ERGNNETVLN NVVPPKEDLD ALLKTFRVQG PVGLEENEKK LLLGWLDAHR KMEKGSMTEE DVQLIQSLEE WEMNDIEGQH THYDLLPGGD EFGVDQDELD AMKEMGF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Forms a fork protection complex (FPC) with TOF1 which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors and protects stalled replication forks against the fork-releasing activity of RRM3 helicase.
基因功能參考文獻：
1. although fork rotation and precatenation facilitate unwinding in hard-to-replicate contexts, they intrinsically disrupt normal chromosome duplication and are therefore restricted by Timeless/Tipin PMID: 26240319
2. The replication stalling complex, Mrc1/Tof1/Csm3, reduces CAG repeat contraction rates independently of replication checkpoint and DNA damage checkpoint factors. PMID: 18321795
3. Ctf19 and Csm3 are both important mediators of pericentromeric cohesion. PMID: 19730685
亞細胞定位：

Nucleus.
蛋白家族：

CSM3 family
數據庫鏈接：

KEGG: sce:YMR048W

STRING: 4932.YMR048W