Recombinant Rat Voltage-dependent anion-selective channel protein 2 (Vdac2), partial

中文名稱：

大鼠Vdac2重組蛋白
貨號：

CSB-YP025824RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Vdac2重組蛋白
貨號：

CSB-EP025824RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Vdac2重組蛋白
貨號：

CSB-EP025824RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Vdac2重組蛋白
貨號：

CSB-BP025824RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Vdac2重組蛋白
貨號：

CSB-MP025824RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Vdac2
Uniprot No.：

P81155
別名：

Vdac2; Voltage-dependent anion-selective channel protein 2; VDAC-2; B36-VDAC; Outer mitochondrial membrane protein porin 2
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol. Binding of ceramide promotes the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway.
基因功能參考文獻：
1. the coupling of VDAC2 with RyR2 is essential for Ca2+ transfer from the sarcoplasmic reticulum to mitochondria in the heart. PMID: 22867515
2. Multiple spots on 2D gel representing VDAC2 protein forms with different isoelectric points. PMID: 19688190
3. Glycogen synthase kinase 3 inhibition slows mitochondrial adenine nucleotide transport and regulates voltage-dependent anion channel phosphorylation. PMID: 18802025
亞細胞定位：

Mitochondrion outer membrane. Membrane.
蛋白家族：

Eukaryotic mitochondrial porin family
組織特異性：

Highly expressed in heart, kidney, brain and ascitic tumor with very low levels in liver. Expressed in the head region of epididymal sperm.
數據庫鏈接：

KEGG: rno:83531

STRING: 10116.ENSRNOP00000018462

UniGene: Rn.162037