Recombinant Rat V-type proton ATPase 116 kDa subunit a isoform 1 (Atp6v0a1), partial

中文名稱：

Recombinant Rat V-type proton ATPase 116 kDa subunit a isoform 1(Atp6v0a1) ,partial
貨號：

CSB-YP002385RA
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat V-type proton ATPase 116 kDa subunit a isoform 1(Atp6v0a1) ,partial
貨號：

CSB-EP002385RA
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat V-type proton ATPase 116 kDa subunit a isoform 1(Atp6v0a1) ,partial
貨號：

CSB-EP002385RA-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat V-type proton ATPase 116 kDa subunit a isoform 1(Atp6v0a1) ,partial
貨號：

CSB-BP002385RA
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat V-type proton ATPase 116 kDa subunit a isoform 1(Atp6v0a1) ,partial
貨號：

CSB-MP002385RA
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Atp6v0a1
Uniprot No.：

P25286
別名：

Atp6v0a1; Atp6n1; Vpp1; V-type proton ATPase 116 kDa subunit a isoform 1; V-ATPase 116 kDa isoform a1; Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit; Vacuolar adenosine triphosphatase subunit Ac116; Vacuolar proton pump subunit 1; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle.
基因功能參考文獻：
1. Mild hypothermia significantly increased V0a1 compared to NT-3 h; V0a1 expression was associated with a decrease in the cleaved caspase 3 expression. These findings suggested that mild hypothermia inhibits CA-induced apoptosis in the hippocampus, which may be associated with reduced V-ATPase impairment. PMID: 27323115
2. V-ATPase membrane domain would allow the exocytotic machinery to discriminate fully loaded and acidified vesicles from vesicles undergoing neurotransmitter reloading. PMID: 24165939
3. Voa1 and Voa2 cooperatively regulate the acidification and transmitter uptake/storage of dense-core vesicles, whereas they might not be as critical for exocytosis as recently proposed. PMID: 21795392
4. alternative splicing of exon N controls differential sorting of a1 variants to nerve terminals or distal dendrites, whereas exon C regulates their neuronal expression PMID: 16621796
亞細胞定位：

Cytoplasmic vesicle membrane; Multi-pass membrane protein. Melanosome. Note=Coated vesicle.
蛋白家族：

V-ATPase 116 kDa subunit family
數(shù)據(jù)庫鏈接：

KEGG: rno:29757

STRING: 10116.ENSRNOP00000052113

UniGene: Rn.6015