Recombinant Rat Protein lifeguard 2 (Faim2), partial

中文名稱：

大鼠Faim2重組蛋白
貨號：

CSB-YP007971RA1
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Faim2重組蛋白
貨號：

CSB-EP007971RA1
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Faim2重組蛋白
貨號：

CSB-EP007971RA1-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Faim2重組蛋白
貨號：

CSB-BP007971RA1
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Faim2重組蛋白
貨號：

CSB-MP007971RA1
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Faim2
Uniprot No.：

O88407
別名：

Faim2; Lfg; Lfg2; Nmp35; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. Plays a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development.
基因功能參考文獻：
1. Data show that NMP35 supports axonal growth, and overexpression of an axonally targeted NMP35 mRNA is sufficient to increase axonal outgrowth. PMID: 23097042
2. expression of Etv5, Faim2, Fto, Negr1 but not Sh2b1 is affected by nutritional state in these two areas, and the relationship between nutritional state and expression levels of obesity-associated genes in two brain areas relevant to feeding. PMID: 22627920
3. NMP35 protein occurs throughout the brain and spinal cord, especially in dendrites of several neuronal cell types and in the surrounding neuropil. NMP35 co-localizes with the glutamate receptor GluR2 and the presynaptic vesicle protein synaptophysin. PMID: 12414123
4. LFG mediated the FasL resistance of cerebellar granular cells to apoptosis PMID: 16033886
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Membrane raft. Cell junction, synapse, postsynaptic cell membrane.
蛋白家族：

BI1 family, LFG subfamily
組織特異性：

Expressed at high levels on dendrites and to a lesser extent on the soma and axons of neurons in various regions of brain.
數據庫鏈接：

KEGG: rno:246274

STRING: 10116.ENSRNOP00000039775

UniGene: Rn.162026