Recombinant Rat Protein-arginine deiminase type-2 (Padi2)

中文名稱：

大鼠Padi2重組蛋白
貨號：

CSB-YP017377RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Padi2重組蛋白
貨號：

CSB-EP017377RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Padi2重組蛋白
貨號：

CSB-EP017377RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Padi2重組蛋白
貨號：

CSB-BP017377RA
規格：
來源：

Baculovirus
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Padi2
Uniprot No.：

P20717
別名：

Padi2; Pad2; Pdi; Pdi2; Protein-arginine deiminase type-2; EC 3.5.3.15; Peptidylarginine deiminase II; Protein-arginine deiminase type II
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區域：

1-665
氨基酸序列

MLRERTVRLQ YGSRVEAVYV LGTQLWTDVY SAAPAGAKTF SLKHSEGVKV EVVRDGEAEE VVTNGKQRWA LSPSTTLRLS MAQASTEASS DKVTVNYYEE DGSAPIDQAG LFLTAIEISL DVDADRDGEV EKNNPKKASW TWGPEGQGAI LLVNCDRDTP WLPKEDCSDE KVYSKQDLQD MSQMILRTKG PDRLPAGYEI VLYISMSDSD KVGVFYVENP FFGQRYIHIL GRQKLYHVVK YTGGSAELLF FVEGLRFPDE SFSGLVSIHV SLLEYMAEDI PLTPIFTDTV TFRIAPWIMT PNILPPVSVF VCCMKDNYLF LKEVKNLVEK TNCELKVCFQ YMNRGDRWIQ DEIEFGYIEA PHKGFPVVLD SPRDGNLKDF PIKQLLGPDF GYVTREPLFE TVTSLDSFGN LEVSPPVTVN GKAYPLGRIL IGSSFPLSGG RRMTKVVRDF LQAQQVQAPV ELYSDWLTVG HVDEFMTFVP IPGKKEFRLL MASTSACYQL FREKQKEGHG EAIMFKGLGG MSSKRITINK ILSNESLTQE NQYFQRCLDW NRDILKKELA LTEKDIIDLP ALFKMDEDRQ ARAFFPNMVN MIVLDKDLGI PKPFGPQVEE ECCLETHVRG LLEPLGLACT FIDDISAYHK FLGEVHCGTN VRRKPFTFKW WHMVP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the deimination of arginine residues of proteins.
基因功能參考文獻：
1. This report revealed the expression of PAD2 by microglia in the prenatal cerebrum at embryonic stages E19-E21. PMID: 17579814
2. The reduced levels of deimination commensurate with reduced protein, mRNA and activity of peptidylarginine deiminase type 2 in the retina. PMID: 18248664
3. Mechanical stretching induced PAD2 expression and consequent protein deimination. PMID: 19085382
4. These biochemical and immunohistochemical results suggest that PAD2 might play an important role in the pathology of early Alzheimer's disease PMID: 19641855
亞細胞定位：

Cytoplasm.
蛋白家族：

Protein arginine deiminase family
組織特異性：

Spinal cord, submaxillary gland, cerebrum, cerebellum, and skeletal muscle.
數據庫鏈接：

KEGG: rno:29511

STRING: 10116.ENSRNOP00000010183

UniGene: Rn.98523