Recombinant Rat Proprotein convertase subtilisin/kexin type 5 (Pcsk5), partial

中文名稱：

大鼠Pcsk5重組蛋白
貨號：

CSB-YP017644RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Pcsk5重組蛋白
貨號：

CSB-EP017644RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Pcsk5重組蛋白
貨號：

CSB-EP017644RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Pcsk5重組蛋白
貨號：

CSB-BP017644RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Pcsk5重組蛋白
貨號：

CSB-MP017644RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Pcsk5
Uniprot No.：

P41413
別名：

Pcsk5; Proprotein convertase subtilisin/kexin type 5; EC 3.4.21.-; Proprotein convertase 5; PC5; Proprotein convertase 6; PC6; Subtilisin/kexin-like protease PC5; rPC5
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors.
基因功能參考文獻：
1. downregulation of Pcsk5 during cloaca development into the rectum and urethra might be related to the formation of anorectal malformations. PMID: 28975535
2. Activation of alpha(v) integrin by proprotein convertase PC5 is necessary for integrin-mediated adhesion and migration by vascular smooth muscle cells (alpha(v) integrin). PMID: 14970114
3. PCSK5A as the gonadotropin-regulated PCSK isoform in the ovary, and its possible contribution to ovulation PMID: 18502031
亞細胞定位：

[Isoform PC5A]: Secreted.; [Isoform PC5B]: Endomembrane system; Single-pass type I membrane protein.
蛋白家族：

Peptidase S8 family
組織特異性：

Expressed in the intestine, brain, adrenal gland, anterior pituitary, thyroid, ovaries, testis and lung. Highest levels are found in the gut, duodenum, jejunum and ileum. Expression is higher in female than in male reproductive organs.
數據庫鏈接：

KEGG: rno:116548

STRING: 10116.ENSRNOP00000016164

UniGene: Rn.104002