Recombinant Rat Kinesin heavy chain isoform 5A (Kif5a), partial

中文名稱：

大鼠Kif5a重組蛋白
貨號：

CSB-YP747521RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Kif5a重組蛋白
貨號：

CSB-EP747521RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Kif5a重組蛋白
貨號：

CSB-EP747521RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Kif5a重組蛋白
貨號：

CSB-BP747521RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Kif5a重組蛋白
貨號：

CSB-MP747521RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Kif5a
Uniprot No.：

Q6QLM7
別名：

Kif5aKinesin heavy chain isoform 5A; Kinesin heavy chain neuron-specific 1; Neuronal kinesin heavy chain; NKHC
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
基因功能參考文獻：
1. The results of this study showed that Microtubule redistribution in growth cones elicited by focal inactivation of kinesin-5 PMID: 22539840
2. kinesin-5 regulates the rate and directionality of neuronal migration and possibly the cessation of migration when the neuron reaches its destination. PMID: 21411631
亞細胞定位：

Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Perikaryon. Note=Concentrated in the cell body of the neurons, particularly in the perinuclear region.
蛋白家族：

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Kinesin subfamily
組織特異性：

Expressed in brain.
數據庫鏈接：

KEGG: rno:314906

STRING: 10116.ENSRNOP00000007721

UniGene: Rn.63144