Recombinant Rat Keratin, type I cytoskeletal 18 (Krt18)

中文名稱：

大鼠Krt18重組蛋白
貨號：

CSB-YP685592RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Krt18重組蛋白
貨號：

CSB-EP685592RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Krt18重組蛋白
貨號：

CSB-EP685592RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Krt18重組蛋白
貨號：

CSB-BP685592RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Krt18
Uniprot No.：

Q5BJY9
別名：

Krt18; Krt1-18Keratin; type I cytoskeletal 18; Cytokeratin-18; CK-18; Keratin-18; K18
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

2-423
氨基酸序列

SFTTRSTTF STNYRSLGSV RTPSQRVRPA SSAASVYAGA GGSGSRISVS RSVWGGSVGS AGLAGMGGVQ TEKETMQDLN DRLASYLDKV KNLETENRRL ESKIREYLEK RGPQGVRDWG HYFKTIEDLR AQIFANSVDN ARIVLQIDNA RLAADDFRVK YETELAMRQS VESDIHGLRK VVDDTNITRL QLETEIEALK EELLFMKKNH EEEVQGLEAQ IASSGLTVEV DAPKSQDLSK IMADIRAQYE QLAQKNREEL DKYWSQQIEE STTVVTTKSA EIRDAETTLL ELRRTLQTLE IDLDSMKNQN INLENNLGEV EARYRVQMEQ LNGVLLHLES ELAQTRAEGQ RQTQEYEALL NIKVKLEAEI ATYRRLLEDG DDFSLNDALD SSNSMQTVQR TTTRKVVDGK VVSETNDTRV LRH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells.
基因功能參考文獻：
1. Resutls show that the appearance caspase-cleaved CK18 in plasma was found to reflect formation of the caspase-cleaved epitope in PMID: 19407366
亞細胞定位：

Nucleus matrix. Nucleus, nucleolus. Cytoplasm.
蛋白家族：

Intermediate filament family
組織特異性：

Expressed on the plasma membrane of hepatocytes and in the narrow apical portions of supporting cells in the vomeronasal sensory epithelium. Detected in the type III alveolar cells of the lung, in the proliferative crypt epithelium of the small intestine
數(shù)據(jù)庫鏈接：

KEGG: rno:294853

STRING: 10116.ENSRNOP00000067234

UniGene: Rn.103924