Recombinant Rat DNA-binding protein RFX2 (Rfx2)

中文名稱：

大鼠Rfx2重組蛋白
貨號：

CSB-YP019611RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Rfx2重組蛋白
貨號：

CSB-EP019611RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Rfx2重組蛋白
貨號：

CSB-EP019611RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Rfx2重組蛋白
貨號：

CSB-BP019611RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Rfx2重組蛋白
貨號：

CSB-MP019611RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rfx2
Uniprot No.：

B2GV50
別名：

Rfx2; DNA-binding protein RFX2; Regulatory factor X 2
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區域：

1-692
氨基酸序列

MQNSEGGADS PATVALRPAA QPVPASPQRV LVQAAGSTPK GTPMQTLTLP RVQPVPPQVQ HVYPAQVQYV EGGDAVYANG AIRAAYTYNP DPQLYAPSSA ASYFETPGGA QVTVAASSPP AVPSHGMVGI TMDVSGTPIV SGAGTYLIHG GMDSTRHSLA HTARSSPATL QWLLDNYETA EGVSLPRSSL YNHYLRHCQE HKLEPVNAAS FGKLIRSVFM GLRTRRLGTR GNSKYHYYGI RLKPDSPLNR LQEDTQYMAM RQQPTHQKPR YRPAQKSDSL GDGSAHSNMH STPEQAMAAQ GQHHQQYIDV SHVFPEFPAP DLGSTLLQES VTLHDVKALQ LVYRRHCEAT LDVVMNLQFQ YIEKLWLSFW NCKATSSDGR ASLPASDEEP EVTLLPKDKL ISLCKCEPIL QWMRSCDHIL YQALVETLIP DVLRPVPSSL TQAIRNFAKS LEGWLINAMS GFPQQVIQTK VGVVSAFAQT LRRYTSLNHL AQAARAVLQN TSQINQMLSD LNRVDFANVQ EQASWVCQCE ESLVQRLEHD FKVTLQQQSS LDQWASWLDN VVTQVLKQHA GSPSFPKAAR QFLLKWSFYS SMVIRDLTLR SAASFGSFHL IRLLYDEYMF YLVEHRVAQA TGETPIAVMG EFNDLASLSL TLLDKEDIGD GHSSEADVDG RSLGEPLVKR ERSDPSHPLQ GI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6.
基因功能參考文獻：
1. These data support the hypothesis that RFX2 expression is upregulated in spermatocytes where it participates in activating transcription of the H1t gene and other testis genes. PMID: 16676351
亞細胞定位：

Nucleus. Cytoplasm.
蛋白家族：

RFX family
組織特異性：

Expressed at highest level in testis. Expressed at lower level in thymus. Also expressed in stomach, kidney, liver, brain and heart. Weakly expressed in spleen and lung. Within testis, most abundantly present in spermatocytes: present from pachytene sperm
數據庫鏈接：

KEGG: rno:301121

STRING: 10116.ENSRNOP00000064610

UniGene: Rn.35756