Recombinant Rat Cytokine-inducible SH2-containing protein (Cish)

中文名稱：

Recombinant Rat Cytokine-inducible SH2-containing protein(Cish)
貨號(hào)：

CSB-YP005445RA
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

Recombinant Rat Cytokine-inducible SH2-containing protein(Cish)
貨號(hào)：

CSB-EP005445RA
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

Recombinant Rat Cytokine-inducible SH2-containing protein(Cish)
貨號(hào)：

CSB-EP005445RA-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Cytokine-inducible SH2-containing protein(Cish)
貨號(hào)：

CSB-BP005445RA
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Cytokine-inducible SH2-containing protein(Cish)
貨號(hào)：

CSB-MP005445RA
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cish
Uniprot No.：

O70512
別名：

CishCytokine-inducible SH2-containing protein; CIS; CIS-1; Suppressor of cytokine signaling; SOCS; Fragment
種屬：

Rattus norvegicus (Rat)
蛋白長(zhǎng)度：

Full length protein
表達(dá)區(qū)域：

1-256
氨基酸序列

VLCVQGSCPL LVVEQIGQRP LWAQSLELPG PAMQPLPTGA FPEEVTEETP VQSENEPKVL DPEGDLLCIA KTFSYLRESG WYWGSITASE ARQHLQKMPE GTFLVRDSTH PSYLFTLSVK TTRGPTNVRI EYADSSFRLD SNCLSRPRIL AFPDVVSLVQ HYVASCTADT RSDSPDPAPT PALPVSKPDA PGDPVLPIPV ATAVHLKLVQ PFVRRSSARS LQHLCRLVIN RLVTDVDCLP LPRRMADYLR QYPFQL
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
數(shù)據(jù)庫(kù)鏈接：

STRING: 10116.ENSRNOP00000041734

UniGene: Rn.14523