Recombinant Rabies virus Phosphoprotein (P)

中文名稱：

Recombinant Rabies virus Phosphoprotein(P)
貨號：

CSB-YP361934RAG
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rabies virus Phosphoprotein(P)
貨號：

CSB-EP361934RAG
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rabies virus Phosphoprotein(P)
貨號：

CSB-EP361934RAG-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rabies virus Phosphoprotein(P)
貨號：

CSB-BP361934RAG
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rabies virus Phosphoprotein(P)
貨號：

CSB-MP361934RAG
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

P
Uniprot No.：

P06747
別名：

P; Phosphoprotein; Protein P; Protein M1
種屬：

Rabies virus (strain Pasteur vaccins / PV) (RABV)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-297
氨基酸序列

MSKIFVNPSA IRAGLADLEM AEETVDLINR NIEDNQAHLQ GEPIEVDNLP EDMGRLHLDD GKSPNPGEMA KVGEGKYRED FQMDEGEDPS LLFQSYLDNV GVQIVRQIRS GERFLKIWSQ TVEEIISYVA VNFPNPPGKS SEDKSTQTTG RELKKETTPT PSQRESQSSK ARMAAQTASG PPALEWSATN EEDDLSVEAE IAHQIAESFS KKYKFPSRSS GILLYNFEQL KMNLDDIVKE AKNVPGVTRL ARDGSKLPLR CVLGWVALAN SKKFQLLVES NKLSKIMQDD LNRYTSC
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body.
基因功能參考文獻(xiàn)：
1. Truncated rabies virus phosphoprotein isoforms promote viral replication in muscle cells through their IFN-beta antagonist activities and thereby support infection of peripheral nerves. PMID: 27384657
2. The phosphoprotein of Rabies viruses isolated rom China shared high similarity in their nucleotide and and amino acid sequences. PMID: 19031691
亞細(xì)胞定位：

[Phosphoprotein]: Virion. Host cytoplasm.; [Isoform P2]: Host cytoplasm.; [Isoform P3]: Host nucleus.; [Isoform P4]: Host nucleus.; [Isoform P5]: Host nucleus.
蛋白家族：

Lyssavirus protein P family
數(shù)據(jù)庫鏈接：

KEGG: vg:1489854