Recombinant Rabbit Macrophage metalloelastase (MMP12)

中文名稱：

小圓錐花果MMP12重組蛋白
貨號：

CSB-YP014659RB
規格：
來源：

Yeast
其他：

中文名稱：

小圓錐花果MMP12重組蛋白
貨號：

CSB-EP014659RB
規格：
來源：

E.coli
其他：

中文名稱：

小圓錐花果MMP12重組蛋白
貨號：

CSB-EP014659RB-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小圓錐花果MMP12重組蛋白
貨號：

CSB-BP014659RB
規格：
來源：

Baculovirus
其他：

中文名稱：

小圓錐花果MMP12重組蛋白
貨號：

CSB-MP014659RB
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MMP12
Uniprot No.：

P79227
別名：

MMP12; Macrophage metalloelastase; MME; EC 3.4.24.65; Matrix metalloproteinase-12; MMP-12
種屬：

Oryctolagus cuniculus (Rabbit)
蛋白長度：

Full length protein
表達區域：

101-464
氨基酸序列

RPVWRKHYIT YRIKNYTPDM KREDVEYAIQ KAFQVWSDVT PLKFRKITTG KADIMILFAS GAHGDYGAFD GRGGVIAHAF GPGPGIGGDT HFDEDEIWSK SYKGTNLFLV AVHELGHALG LDHSNDPKAI MFPTYGYIDL NTFHLSADDI RGIQSLYGGP EQHQPMPKPD NPEPTACDHN LKFDAVTTVG NKIFFFKDSF FWWKIPKSST TSVRLISSLW PTLPSGIEAA YEIGDRHQVF LFKGDKFWLI SHLRLQPNYP KSIHSLGFPD FVKKIDAAVF NPSLRKTYFF VDNLYWRYDE RREVMDAGYP KLITKHFPGI GPKIDAVFYF QRYYYFFQGP NQLEYDTFSS RVTKKLKSNS WFDC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
基因功能參考文獻：
1. Gene expression profiling performed on tissues obtained from pulmonary sarcoidosis patients identified MMP12 as a potential pathogenic mediator of lung damage and/or remodeling and may serve as a marker for this disease. PMID: 19218196
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Peptidase M10A family
數據庫鏈接：

KEGG: ocu:100009559

STRING: 9986.ENSOCUP00000007180

UniGene: Ocu.2122