Recombinant Pig Fatty acid-binding protein, heart (FABP3)

中文名稱：

野豬FABP3重組蛋白
品名簡稱：

Recombinant Pig FABP3 protein
貨號：

CSB-EP007943PI
說明書：

MSDS Datasheet
規格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

FABP3
Uniprot No.：

O02772
別名：

Fatty acid-binding protein 3 (Heart-type fatty acid-binding protein) (H-FABP)
種屬：

Sus scrofa (Pig)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

22.1 kDa
表達區域：

2-133aa
氨基酸序列

VDAFAGTWKLVDSKNFDDYMKSIGVGFATRQVANMTKPTTIIEVNGDTIIIKTQSTFKSTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWNGQETTLVRELVDGKLILTLTHGSAVCTRTYEKEA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis and C-terminal myc-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

13-23 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
基因功能參考文獻：
1. SNPs in the FABP3 promoter may contribute to intramuscular fat without influencing carcass fatness traits in pigs PMID: 25306509
2. Expression of the FABP3 gene enhances adipogenesis in 3T3-L1 preadipocytes primarily by upregulating lipogenic genes. PMID: 24737696
3. Results indicate that fatty acid binding protein H-FABP and CoA ligase 4 ACSL4 genes might serve as markers to improve fat (IMF) content in the breeding system. PMID: 25177956
4. hFABP rises faster and correlates better with infarct size and no-reflow than hsTnI in myocardial infarction + reperfusion when measured early after reperfusion. PMID: 23873799
5. Linkage disequilibrium analysis among MC4R, LEP and H-FABP revealed that these genes were independent. PMID: 22290286
6. The FABP3 polymorphisms can be used as genetic markers in breeding programs for intramuscular fat content as well as carcass back fat thickness. PMID: 20848210
7. The H-FABP MspI RFLP genotype affected unsaturated fatty acid content, and the ratio of polyunsaturated fatty acid to saturated fatty acid (P<0.05), whereas the H-FABP HaeIII RFLP genotype had no effect on fatty acid characteristics. PMID: 20659784
8. The objective of this study was to investigate the effect of FABP3 and LEPR genetic variations as well as their mRNA expression on the intramuscular fat content trait in a three-generation of Korean native pig and Yorkshire crossed animals. PMID: 20300864
9. Results of associated analysis show that the polymorphism of H-FABP gene was associated traits of Intramuscular fat content (IMF) and back fat thickness (BF). PMID: 16520310
10. In our study FABP3 genotypes were confirmed to be significantly associated with intramuscular fat in pigs. PMID: 16706925
11. Sirt1 regulates the expression of FABP3 gene in adipocytes, and PPAR gamma apparently plays an important role in this process. PMID: 19479941
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亞細胞定位：

Cytoplasm.
蛋白家族：

Calycin superfamily, Fatty-acid binding protein (FABP) family
數據庫鏈接：

KEGG: ssc:399532

STRING: 9823.ENSSSCP00000003898

UniGene: Ssc.78656