Recombinant Pig Cholesterol 7-alpha-monooxygenase (CYP7A1), partial

中文名稱：

Recombinant Pig Cholesterol 7-alpha-monooxygenase(CYP7A1) ,partial
貨號：

CSB-YP006460PI
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Pig Cholesterol 7-alpha-monooxygenase(CYP7A1) ,partial
貨號：

CSB-EP006460PI
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Pig Cholesterol 7-alpha-monooxygenase(CYP7A1) ,partial
貨號：

CSB-EP006460PI-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Pig Cholesterol 7-alpha-monooxygenase(CYP7A1) ,partial
貨號：

CSB-BP006460PI
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Pig Cholesterol 7-alpha-monooxygenase(CYP7A1) ,partial
貨號：

CSB-MP006460PI
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CYP7A1
Uniprot No.：

O46491
別名：

CYP7A1; CYP7Cytochrome P450 7A1; 24-hydroxycholesterol 7-alpha-hydroxylase; EC 1.14.14.26; CYPVII; Cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; EC 1.14.14.23
種屬：

Sus scrofa (Pig)
蛋白長度：

Partial
表達區域：

1-501
氨基酸序列

MMSISLLGGI VTAVCCCLWL LLGMRRRQTG EPPLENGIIP YLGCALQFGA NPLEFLRANQ RKHGHIFTCQ LMGNYVHFIT NPLSYHKVLC HGKYLDWKKF HFTASAKAFG HRSIDPSDGN TTDNINKTII KTLQGDALNL LAAAMMENLQ LVLRPQVAPQ PEKPAWVTEG MYSFCYRVMF EAGYVTLFGK DPIGHDAQKA LILNNLDNFK QFDKIFPALV AGFPIHVFKT GHYAREKLAE GLRLQKLRKR DHISELVRFL NDTLSTLDDA EKAKSLLAVL WASQANTIPA TFWCLFQTIR SPEAMKAASE EVNKTLEKAG QKISLDDKPI YLNQIELDSM PVLDSIIKES LRLSSASLNI RTAKEDFTLH LQDGSYNIRK DDIIALYPQL MHLDPEIYPD PLTFKYDRYL DENGKTKTTF YSHGLKLKYY YMPFGSGATI CPGRLFAVQE IKQFLILMLS YFDLELVESH VKCPPLDQSR AGLGILPPSN DIEFRYKLKH L
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting step in cholesterol catabolism and bile acid biosynthesis. 7-alpha hydroxylates several oxysterols, including 4beta-hydroxycholesterol and 24-hydroxycholesterol. Catalyzes the oxidation of the 7,8 double bond of 7-dehydrocholesterol and lathosterol with direct and predominant formation of the 7-keto derivatives.
亞細胞定位：

Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
蛋白家族：

Cytochrome P450 family
數據庫鏈接：

STRING: 9823.ENSSSCP00000006650

UniGene: Ssc.30521