Recombinant Pig 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), partial

中文名稱：

野豬HMGCR重組蛋白
貨號：

CSB-YP010565PI
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

野豬HMGCR重組蛋白
貨號：

CSB-EP010565PI
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

野豬HMGCR重組蛋白
貨號：

CSB-EP010565PI-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

野豬HMGCR重組蛋白
貨號：

CSB-BP010565PI
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

野豬HMGCR重組蛋白
貨號：

CSB-MP010565PI
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HMGCR
Uniprot No.：

Q1W675
別名：

HMGCR; HMGR; 3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase; EC 1.1.1.34
種屬：

Sus scrofa (Pig)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis.
基因功能參考文獻：
1. HMGCR inhibits the early stage of PCV2 infection, while PKC enhances the infection at the late stage. PMID: 28017735
2. The relative expression level of HMGR was high in liver, heart, kidney, bladder and subcutaneous fat, medium in lung, uterus and large intestine, and low in cerebrum, spleen, spinal cord, stomach, ovary, longissimus muscle, and small intestine. PMID: 22240315
亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein.
蛋白家族：

HMG-CoA reductase family
組織特異性：

High expression found in liver, heart, kidney, bladder and subcutaneous fat. Lower levels in lung, uterus and large intestine. Lowest levels in cerebrum, spleen, spinal cord, stomach, ovary, longissimus muscle, and small intestine.
數據庫鏈接：

KEGG: ssc:100144446

STRING: 9823.ENSSSCP00000014973

UniGene: Ssc.97427