Recombinant Paralyzed arrest at two-fold protein 6 (pat-6)

中文名稱：

秀麗隱桿線蟲pat-6重組蛋白
貨號：

CSB-YP522702CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲pat-6重組蛋白
貨號：

CSB-EP522702CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲pat-6重組蛋白
貨號：

CSB-EP522702CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲pat-6重組蛋白
貨號：

CSB-BP522702CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲pat-6重組蛋白
貨號：

CSB-MP522702CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

pat-6
Uniprot No.：

O16785
別名：

pat-6; T21D12.4; Paralyzed arrest at two-fold protein 6; Actopaxin homolog; Parvin-like protein
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-375
氨基酸序列

MSTLGRSKTP SRDEPKKPGV FEKLSGTLSR KKKAPEDEHG NQGGAHHATD EDEVLELELE GREALDQSLV PVLARNIWLE EGEIRRYLTK ETARDQKLAQ VVDLLIYWLN EELADQRIVV RHLQEDLFDG QIIQKLLEKL EQIRIEVPEV SQSEEGQRQK LQIVVQTANR ILGQPREQEK WSADLIHQKD FTAIIQLLVL LALHYRAPVR FPDNVVANVV VAQKEHGQVK THRITEQITT VQTELAPKGT RDAFDTLFDY GPDKLAHVKT SLLAFCNKHL NKINLEVSDL DNQFQDGVFL VLLVGLLEGY FVPLYHFNLQ VQSHEEKVKN VQFAFKLMED TGLEKPRSRV QDIANGDVKS TLRLLHLLFT KYKHI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the regulation of cell adhesion and cytoskeleton organization. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. During embryonic development, required to recruit cpna-1, unc-89 and myofilaments to newly forming integrin attachments composed of integrins pat-2/pat-3, pat-4 and unc-112. Also required to reposition the integrin-based attachments so that they form the highly ordered array of dense body and M-line attachments that are characteristic of mature muscle cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles.
基因功能參考文獻：
1. PAT-6/actopaxin plays essential roles during the maturation of integrin-mediated muscle attachments in vivo. PMID: 12781130
亞細胞定位：

Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, M line. Perikaryon. Cell projection, axon.
蛋白家族：

Parvin family
組織特異性：

Expressed from 1.5 stage embryos, mostly within the muscle cells. In adult hermaphrodites, expressed in the attachments of other muscles, including the uterine, anal depressor, anal sphincter, and vulval muscles, as well as in the spermatheca and the dist
數據庫鏈接：

KEGG: cel:CELE_T21D12.4

STRING: 6239.T21D12.4.2

UniGene: Cel.12540